Fig. 4
Concurrent delivery of mechanical and electrical stimulation had negligible impact on independent mechanical and electrical calibrations. (a) There was no significant difference between mechanical strains measured during independent or concurrent stimulation (p > 0.05). (b) There was no significant difference in electrical voltages measured during independent or concurrent stimulation (p > 0.05). Thus, it appears that the mechanical stimulation is unaffected by concurrent electrical stimulation, and vice versa, allowing precise stimuli to be delivered either independently or in combination. Mechanical data show peak strains at each of the strain magnitudes, averaged across the six growth channels. Electrical data show the peak voltage (averaged from multiple cycles during the time to complete mechanical stimulation), in each of the growth channels. The negative strains observed at 0.0% are likely due to small vertical displacement at the growth channel center resulting from recording electrode placement. Mean ± SD; n = 6.

Concurrent delivery of mechanical and electrical stimulation had negligible impact on independent mechanical and electrical calibrations. (a) There was no significant difference between mechanical strains measured during independent or concurrent stimulation (p > 0.05). (b) There was no significant difference in electrical voltages measured during independent or concurrent stimulation (p > 0.05). Thus, it appears that the mechanical stimulation is unaffected by concurrent electrical stimulation, and vice versa, allowing precise stimuli to be delivered either independently or in combination. Mechanical data show peak strains at each of the strain magnitudes, averaged across the six growth channels. Electrical data show the peak voltage (averaged from multiple cycles during the time to complete mechanical stimulation), in each of the growth channels. The negative strains observed at 0.0% are likely due to small vertical displacement at the growth channel center resulting from recording electrode placement. Mean ± SD; n = 6.

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