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Z. Hugh Fan
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Proceedings Papers

Integration of Minivalves With RNA Amplification Device for Simultaneous Detection of SARS-CoV-2 and Influenza Viruses

Morteza Alipanah, Carlos Manzanas, John A. Lednicky, Chang-Yu Wu, Z. Hugh Fan
Proc. ASME. IMECE2022, Volume 4: Biomedical and Biotechnology; Design, Systems, and Complexity, V004T05A011, October 30–November 3, 2022
Paper No: IMECE2022-96831
https://doi.org/10.1115/IMECE2022-96831
View Paper titled, Integration of Minivalves With RNA Amplification Device for Simultaneous Detection of SARS-CoV-2 and Influenza Viruses
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Topics: RNA, Valves, Microfluidics
Proceedings Papers

Microfluidic Devices for Isolating and Releasing Disseminated Tumor Cells in Bone Marrow

Minh-Chau N. Le, Dongjiang Chen, Kierstin A. Smith, David D. Tran, Z. Hugh Fan
Proc. ASME. IMECE2022, Volume 9: Mechanics of Solids, Structures, and Fluids; Micro- and Nano-Systems Engineering and Packaging; Safety Engineering, Risk, and Reliability Analysis; Research Posters, V009T13A004, October 30–November 3, 2022
Paper No: IMECE2022-94554
https://doi.org/10.1115/IMECE2022-94554
View Paper titled, Microfluidic Devices for Isolating and Releasing Disseminated Tumor Cells in Bone Marrow
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Topics: Bone, Cancer, Microfluidics, Tumors
Proceedings Papers

Valve-Enabled Sample Preparation and Isothermal Amplification for SARS-CoV-2 Detection at the Point-of-Care

Carlos Manzanas, Md. Mahbubul Alam, Julia C. Loeb, John A. Lednicky, Chang-Yu Wu, Z. Hugh Fan
Proc. ASME. IMECE2021, Volume 12: Mechanics of Solids, Structures, and Fluids; Micro- and Nano- Systems Engineering and Packaging, V012T13A001, November 1–5, 2021
Paper No: IMECE2021-69303
https://doi.org/10.1115/IMECE2021-69303
View Paper titled, Valve-Enabled Sample Preparation and Isothermal Amplification for SARS-CoV-2 Detection at the Point-of-Care
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Topics: Valves, RNA, Diseases, Heat, Testing
Proceedings Papers

Development of Ball-Enabled Miniaturized Valves for Sample Preparation and Microheaters for Pathogen Detection

Carlos Manzanas, Xiao Jiang, John A. Lednicky, Z. Hugh Fan
Proc. ASME. FEDSM2020, Volume 3: Computational Fluid Dynamics; Micro and Nano Fluid Dynamics, V003T06A003, July 13–15, 2020
Paper No: FEDSM2020-20379
https://doi.org/10.1115/FEDSM2020-20379
View Paper titled, Development of Ball-Enabled Miniaturized Valves for Sample Preparation and Microheaters for Pathogen Detection
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Topics: Valves, RNA, Testing, Fluids, Poles (Building), Storage, Temperature
Proceedings Papers

Capillary Force Driven Single-Cell Spiking Apparatus for Studying Circulating Tumor Cells

Jacob Amontree, Kangfu Chen, Jose Varillas, Z. Hugh Fan
Proc. ASME. IMECE2018, Volume 10: Micro- and Nano-Systems Engineering and Packaging, V010T13A016, November 9–15, 2018
Paper No: IMECE2018-87109
https://doi.org/10.1115/IMECE2018-87109
View Paper titled, Capillary Force Driven Single-Cell Spiking Apparatus for Studying Circulating Tumor Cells
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Topics: Tumors, Blood, Cancer, Biomedicine, Membranes, Reliability, Separation (Technology)
Proceedings Papers

Interactions Between Circulating Tumor Cells and Aptamer-Functionalized Microposts in a Flow

Kangfu Chen, Teodor Georgiev, Z. Hugh Fan
Proc. ASME. IMECE2017, Volume 7: Fluids Engineering, V007T09A045, November 3–9, 2017
Paper No: IMECE2017-70342
https://doi.org/10.1115/IMECE2017-70342
View Paper titled, Interactions Between Circulating Tumor Cells and Aptamer-Functionalized Microposts in a Flow
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Topics: Flow (Dynamics), Tumors, Microfluidics, Simulation, Blood, Cancer, Design, Geometry, Shear stress
Proceedings Papers

Development of All-Plastic Microvalve Array for Multiplexed Immunoassay

Shancy Augustine, Pan Gu, Xiangjun Zheng, Toshikazu Nishida, Z. Hugh Fan
Proc. ASME. IMECE2014, Volume 10: Micro- and Nano-Systems Engineering and Packaging, V010T13A045, November 14–20, 2014
Paper No: IMECE2014-38154
https://doi.org/10.1115/IMECE2014-38154
View Paper titled, Development of All-Plastic Microvalve Array for Multiplexed Immunoassay
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Topics: Assaying, Batteries, Carbon reinforced plastics, Copolymers, Energy consumption, Engineering prototypes, Flow (Dynamics), Food products, Microfluidics, Paraffin wax
Proceedings Papers

Microfluidic Valve Arrays in Thermoplastic Devices

Z. Hugh Fan, Pan Gu, Shancy Augustine, Ke Liu, Harvy Freitag, Toshikazu Nishida
Proc. ASME. ICNMM2012, ASME 2012 10th International Conference on Nanochannels, Microchannels, and Minichannels, 453-458, July 8–12, 2012
Paper No: ICNMM2012-73021
https://doi.org/10.1115/ICNMM2012-73021
View Paper titled, Microfluidic Valve Arrays in Thermoplastic Devices
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Topics: Microfluidics, Valves, Plasma desorption mass spectrometry, Elastomers, Separation (Technology), Biocompatibility, Blocks (Building materials), Bonding, Contamination, Copolymers
Proceedings Papers

Thermally Actuated Plastic Microfluidic Valves

Pan Gu, Karthik Pitchaiman, Ke Liu, Toshikazu Nishida, Z. Hugh Fan
Proc. ASME. IMECE2010, Volume 10: Micro and Nano Systems, 729-733, November 12–18, 2010
Paper No: IMECE2010-38041
https://doi.org/10.1115/IMECE2010-38041
View Paper titled, Thermally Actuated Plastic Microfluidic Valves
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Topics: Microfluidics, Valves, Temperature, Design, Fluids, Separation (Technology), Control equipment, Copolymers, Deflection, Fluid dynamics
Proceedings Papers

Microfluidic Reactors for Bioluminescence Detection

Z. Hugh Fan, Qian Mei, Steve Soper
Proc. ASME. IMECE2009, Volume 12: Micro and Nano Systems, Parts A and B, 773-778, November 13–19, 2009
Paper No: IMECE2009-12464
https://doi.org/10.1115/IMECE2009-12464
View Paper titled, Microfluidic Reactors for Bioluminescence Detection
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Topics: Microfluidics, Enzymes, Calibration, Embossing, Flow (Dynamics), Micromilling, Theoretical analysis
Proceedings Papers

Microfluidic Devices for Rapid Protein Separation

Z. Hugh Fan, Champak Das, Cesar Moreira, Daniel Olivero, Hong Chen
Proc. ASME. MICRONANO2008, 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems, 513-516, June 3–5, 2008
Paper No: MicroNano2008-70208
https://doi.org/10.1115/MicroNano2008-70208
View Paper titled, Microfluidic Devices for Rapid Protein Separation
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Topics: Microfluidics, Proteins, Separation (Technology), Polymers, Coating processes, Coatings, Copolymers, Electric fields, Electroosmosis, Electrophoresis
Proceedings Papers

Fluid Mixing in Channels With Microridges

Zheng Xia, Lou Cattafesta, Mark Sheplak, Renwei Mei, Z. Hugh Fan
Proc. ASME. IMECE2007, Volume 11: Micro and Nano Systems, Parts A and B, 139-142, November 11–15, 2007
Paper No: IMECE2007-43052
https://doi.org/10.1115/IMECE2007-43052
View Paper titled, Fluid Mixing in Channels With Microridges
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Topics: Fluids, Flow (Dynamics), Computational fluid dynamics, Fluid dynamics, Fluorescence, Microchannels, Microscopy, Molding, Photolithography, Simulation
Proceedings Papers

Fabricating Plastic Microfluidic Devices With Photodefinable Microvalves for Protein Separations

Carl K. Fredrickson, Champak Das, Fernando T. Tavares, Ryan Ferguson, Zheng Xia, Z. Hugh Fan
Proc. ASME. IMECE2005, Microelectromechanical Systems, 3-7, November 5–11, 2005
Paper No: IMECE2005-79229
https://doi.org/10.1115/IMECE2005-79229
View Paper titled, Fabricating Plastic Microfluidic Devices With Photodefinable Microvalves for Protein Separations
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Topics: Microfluidics, Molding, Polymerization, Proteins, Separation (Technology)
Proceedings Papers

Fabricating a Plastic Microfluidic Device for Protein Synthesis

Qian Mei, Carl K. Fredrickson, Andrew Simon, Z. Hugh Fan
Proc. ASME. IMECE2006, Microelectromechanical Systems, 33-37, November 5–10, 2006
Paper No: IMECE2006-14122
https://doi.org/10.1115/IMECE2006-14122
View Paper titled, Fabricating a Plastic Microfluidic Device for Protein Synthesis
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Topics: Microfluidics, Proteins