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Proceedings Papers

Platelet Activation in Flow Past Mechanical Heart Valves

Danny Bluestein, Jolyon Jesty, Adam E. Saltman, Irvin B. Krukenkamp, Krishnamurthy Suresh
Proc. ASME. IMECE2001, Advances in Bioengineering, 221-222, November 11–16, 2001
Paper No: IMECE2001/BED-23110
https://doi.org/10.1115/IMECE2001/BED-23110
View Paper titled, Platelet Activation in Flow Past Mechanical Heart Valves
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Topics: Flow (Dynamics), Heart valve prostheses, Platelets, Valves, Shear stress, Turbulence, Vortices, Biomedicine, Jets, Orifices
Proceedings Papers

E-Selectin Expression on Endothelial Cells in the Presence of Platelets and Cigarette Smoke Extract

Gaurav Girdhar, Sulan Xu, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 871-872, June 25–29, 2008
Paper No: SBC2008-192154
https://doi.org/10.1115/SBC2008-192154
View Paper titled, E-Selectin Expression on Endothelial Cells in the Presence of Platelets and Cigarette Smoke Extract
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Topics: Endothelial cells, Platelets, Smoke, Risk, Shear stress, Adhesion, Cardiovascular system, Diseases, Hemodynamics, Physiology
Proceedings Papers

Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study

Jawaad Sheriff, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 825-826, June 25–29, 2008
Paper No: SBC2008-192561
https://doi.org/10.1115/SBC2008-192561
View Paper titled, Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study
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Topics: Damage, Hemodynamics, Platelets, Shear stress, Blood flow, Die cutting, Flow (Dynamics), Heart valve prostheses, Optimization, Prostheses
Proceedings Papers

Progressive Increase in Platelet Activation With Smoke Exposure: Human Subject and In-Vitro Studies

Gaurav Girdhar, Sulan Xu, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 463-464, June 20–24, 2007
Paper No: SBC2007-176018
https://doi.org/10.1115/SBC2007-176018
View Paper titled, Progressive Increase in Platelet Activation With Smoke Exposure: Human Subject and In-Vitro Studies
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Topics: Platelets, Smoke, Diseases, Cardiovascular system, Chemical vapor deposition, Damage, Physiology, Risk
Proceedings Papers

In Vitro Evaluation of Shear-Induced Platelet Activation in the MicroMed DeBakey Ventricular Assist Device With Antiplatelet Therapy

Jawaad Sheriff, Gaurav Girdhar, Sheela George, Wei-Che Chiu, Bryan E. Lynch, Jolyon Jesty, Marvin J. Slepian, Danny Bluestein
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT05A003, June 26–29, 2013
Paper No: SBC2013-14088
https://doi.org/10.1115/SBC2013-14088
View Paper titled, In Vitro Evaluation of Shear-Induced Platelet Activation in the MicroMed DeBakey Ventricular Assist Device With Antiplatelet Therapy
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Topics: Patient treatment, Platelets, Shear (Mechanics), Ventricular assist devices, Thrombosis, Bridges (Structures), Design, Flow (Dynamics), Heart failure, Optimization
Proceedings Papers

Dynamic Shear Stress Induced Platelet Activation in Blood Recirculation Devices: Implications for Thrombogenicity Minimization

Gaurav Girdhar, Jawaad Sheriff, Michalis Xenos, Yared Alemu, Thomas Claiborne, Marvin Slepian, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 231-232, June 17–21, 2009
Paper No: SBC2009-206353
https://doi.org/10.1115/SBC2009-206353
View Paper titled, Dynamic Shear Stress Induced Platelet Activation in Blood Recirculation Devices: Implications for Thrombogenicity Minimization
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Topics: Blood, Platelets, Shear stress, Flow (Dynamics), Artificial hearts, Blood flow, Bridges (Structures), Cardiovascular system, Design, Diseases
Proceedings Papers

Development and Optimization of a Novel Polymeric Prosthetic Heart Valve Using the Device Thrombogenicity Emulation (DTE) Methodology

Thomas E. Claiborne, Michalis Xenos, Jawaad Sheriff, Dinesh Peter, Yared Alemu, Yasushi Kato, Leonard Pinchuk, Shmuel Einav, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 465-466, June 20–23, 2012
Paper No: SBC2012-80186
https://doi.org/10.1115/SBC2012-80186
View Paper titled, Development and Optimization of a Novel Polymeric Prosthetic Heart Valve Using the Device Thrombogenicity Emulation (DTE) Methodology
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Topics: Heart valve prostheses, Optimization, Valves, Diseases, Biological tissues, Surgery, Artificial hearts, Biocompatibility, Patient treatment
Proceedings Papers

Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments

Jawaad Sheriff, Michalis Xenos, João S. Soares, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 883-884, June 20–23, 2012
Paper No: SBC2012-80134
https://doi.org/10.1115/SBC2012-80134
View Paper titled, Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments
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Topics: Platelets, Shear stress, Blood, Flow (Dynamics), Shear (Mechanics), Diseases, Heart failure, Heart valve prostheses, Optimization, Patient treatment
Proceedings Papers

Thrombogenicity Comparison of Axial Ventricular Assist Devices by DTE Methodology: MicroMed HeartAssist 5 and Thoratec Heartmate II

Wei-Che Chiu, Michalis Xenos, Yared Alemu, Gaurav Girdhar, Bryan Lynch, Jolyon Jesty, Marvin Slepian, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 63-64, June 20–23, 2012
Paper No: SBC2012-80190
https://doi.org/10.1115/SBC2012-80190
View Paper titled, Thrombogenicity Comparison of Axial Ventricular Assist Devices by DTE Methodology: MicroMed HeartAssist 5 and Thoratec Heartmate II
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Topics: Ventricular assist devices, Blood flow, Bridges (Structures), Cardiovascular system, Design, Diseases, Flow (Dynamics), Heart failure, Hemodynamics, Patient treatment
Proceedings Papers

Evaluation of Syncardia Total Artificial Heart Using Device Thrombogenicity Emulator

Yared Alemu, Gaurav Girdhar, Michalis Xenos, Thomas Claiborne, Jolyon Jesty, Shmuel Einav, Marvin Slepian, Danny Bluestein
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 163-164, June 22–25, 2011
Paper No: SBC2011-53420
https://doi.org/10.1115/SBC2011-53420
View Paper titled, Evaluation of Syncardia Total Artificial Heart Using Device Thrombogenicity Emulator
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Topics: Artificial hearts, Platelets, Stress, Fluid structure interaction, Simulation, Cardiac cycle, Computer simulation, Computers, Density, Design
Proceedings Papers

Design Optimization of Rotary Blood Pumps: Alternatives to Anticoagulation Therapy

Gaurav Girdhar, Michalis Xenos, Wei-Che Chiu, Yared Alemu, Bryan Lynch, Jolyon Jesty, Marvin Slepian, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 173-174, June 22–25, 2011
Paper No: SBC2011-53171
https://doi.org/10.1115/SBC2011-53171
View Paper titled, Design Optimization of Rotary Blood Pumps: Alternatives to Anticoagulation Therapy
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Topics: Blood, Design, Optimization, Patient treatment, Pumps, Platelets, Bridges (Structures), Computer simulation, Flow (Dynamics), Heart failure
Proceedings Papers

Dynamic Numerical and Experimental Evaluation of Trileaflet Polymer Prosthetic Heart Valves

Thomas E. Claiborne, Michalis Xenos, Gaurav Girdhar, Yared Alemu, Jawaad Sheriff, Marvin Slepian, Leonard Pinchuk, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1205-1206, June 22–25, 2011
Paper No: SBC2011-53176
https://doi.org/10.1115/SBC2011-53176
View Paper titled, Dynamic Numerical and Experimental Evaluation of Trileaflet Polymer Prosthetic Heart Valves
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Topics: Heart valve prostheses, Polymers, Valves, Artificial hearts, Biological tissues, Diseases, Durability, Food and Drug Administration, Frequency-domain analysis, Hemodynamics
Proceedings Papers

Design Optimization of a Mechanical Heart Valve for Reducing Valve Thrombogenicity: A Case Study With ATS Valve

Gaurav Girdhar, Yared Alemu, Michalis Xenos, Jawaad Sheriff, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 277-278, June 16–19, 2010
Paper No: SBC2010-19309
https://doi.org/10.1115/SBC2010-19309
View Paper titled, Design Optimization of a Mechanical Heart Valve for Reducing Valve Thrombogenicity: A Case Study With ATS Valve
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Topics: Design, Heart valve prostheses, Optimization, Valves, Flow (Dynamics), Artificial hearts, Patient treatment, Physiology, Platelets, Risk
Proceedings Papers

In-Vitro Thrombogenicity Assessment of Mechanical Circulatory Support Devices and Prosthetic Heart Valves

Thomas E. Claiborne, Gaurav Girdhar, Jawaad Sheriff, Jolyon Jesty, Marvin J. Slepian, Robert Benkowski, Leonard Pinchuk, Danny Bluestein
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 115-116, June 16–19, 2010
Paper No: SBC2010-19287
https://doi.org/10.1115/SBC2010-19287
View Paper titled, In-Vitro Thrombogenicity Assessment of Mechanical Circulatory Support Devices and Prosthetic Heart Valves
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Topics: Heart valve prostheses, Platelets, Artificial hearts, Blood, Bridges (Structures), Engineering prototypes, Flow (Dynamics), Heart failure, Impellers, Patient treatment
Proceedings Papers

Platelet Activation and Free Emboli Formation in Flow Past Mechanical Heart Valves

Danny Bluestein, Wei Yin, Jolyon Jesty, Adam E. Saltman, Irvin B. Krukenkamp, Oscar Bernal, Krishnamurthy Suresh
Proc. ASME. IMECE2002, Advances in Bioengineering, 269-270, November 17–22, 2002
Paper No: IMECE2002-32288
https://doi.org/10.1115/IMECE2002-32288
View Paper titled, Platelet Activation and Free Emboli Formation in Flow Past Mechanical Heart Valves
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Topics: Flow (Dynamics), Heart valve prostheses, Platelets, Valves, Shear stress, Turbulence, Vortices, Biomedicine, Carotid arteries, Jets
Proceedings Papers

Effects of Valve Design and Orientation on Flow Induced Platelet Activation in Mechanical Heart Valves

Wei Yin, Yared Alemu, Jolyon Jesty, Danny Bluestein
Proc. ASME. IMECE2004, Advances in Bioengineering, 37-38, November 13–19, 2004
Paper No: IMECE2004-61336
https://doi.org/10.1115/IMECE2004-61336
View Paper titled, Effects of Valve Design and Orientation on Flow Induced Platelet Activation in Mechanical Heart Valves
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Topics: Design, Flow (Dynamics), Heart valve prostheses, Platelets, Valves, Shear stress, Computational fluid dynamics, Turbulence, Blood flow, Engineering simulation