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Proceedings Papers

Risk of Rupture in Abdominal Aortic Aneurysms and Vulnerable Plaques: A Patient Based Fluid Structure Interaction Approach

Danny Bluestein, Yared Alemu, Michalis Xenos, Peter Rissland, Jawaad Sheriff, Luis Gruberg, Shmuel Einav, John J. Ricotta
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 891-892, June 25–29, 2008
Paper No: SBC2008-192828
https://doi.org/10.1115/SBC2008-192828
View Paper titled, Risk of Rupture in Abdominal Aortic Aneurysms and Vulnerable Plaques: A Patient Based Fluid Structure Interaction Approach
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Topics: Aneurysms, Fluid structure interaction, Risk, Rupture, Engineering simulation, Simulation, Stress, Anisotropy, Geometry, Deformation
Proceedings Papers

Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study

Jawaad Sheriff, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 825-826, June 25–29, 2008
Paper No: SBC2008-192561
https://doi.org/10.1115/SBC2008-192561
View Paper titled, Platelet Damage Accumulation and Recovery due to Hemodynamic Shear Stresses: An In Vitro Study
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Topics: Damage, Hemodynamics, Platelets, Shear stress, Blood flow, Die cutting, Flow (Dynamics), Heart valve prostheses, Optimization, Prostheses
Proceedings Papers

Identification of a Mathematical Model for the Prediction of Platelet Damage Accumulation in Artificial Organs: A Preliminary Study

Matteo Nobili, Jawaad Sheriff, Umberto Morbiducci, Alberto Redaelli, Danny Bluestein
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 705-706, June 20–24, 2007
Paper No: SBC2007-176165
https://doi.org/10.1115/SBC2007-176165
View Paper titled, Identification of a Mathematical Model for the Prediction of Platelet Damage Accumulation in Artificial Organs: A Preliminary Study
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Topics: Artificial organs, Damage, Platelets, Blood, Bridges (Structures), Computer simulation, Die cutting, Flow (Dynamics), Gases, Genetic algorithms
Proceedings Papers

Platelet Activity State in Human, Bovine, and Ovine Species Under Constant Shear Stress: A Comparative Study

Phat L. Tran, Valerie M. Merkle, Tracy DeCook, Marcus Hutchinson, Jawaad Sheriff, Danny Bluestein, Marvin J. Slepian
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT03A006, June 26–29, 2013
Paper No: SBC2013-14825
https://doi.org/10.1115/SBC2013-14825
View Paper titled, Platelet Activity State in Human, Bovine, and Ovine Species Under Constant Shear Stress: A Comparative Study
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Topics: Platelets, Shear stress, Artificial hearts, Blood, Bridges (Structures), Cardiovascular devices, Design, Heart failure, Patient treatment, Ventricular assist devices
Proceedings Papers

In Vitro Evaluation of Shear-Induced Platelet Activation in the MicroMed DeBakey Ventricular Assist Device With Antiplatelet Therapy

Jawaad Sheriff, Gaurav Girdhar, Sheela George, Wei-Che Chiu, Bryan E. Lynch, Jolyon Jesty, Marvin J. Slepian, Danny Bluestein
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT05A003, June 26–29, 2013
Paper No: SBC2013-14088
https://doi.org/10.1115/SBC2013-14088
View Paper titled, In Vitro Evaluation of Shear-Induced Platelet Activation in the MicroMed DeBakey Ventricular Assist Device With Antiplatelet Therapy
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Topics: Patient treatment, Platelets, Shear (Mechanics), Ventricular assist devices, Thrombosis, Bridges (Structures), Design, Flow (Dynamics), Heart failure, Optimization
Proceedings Papers

Platelet Activity of Coaxial Electrospun Scaffolds for Applications in Cardiovascular Tissue Engineering

Valerie M. Merkle, Marcus Hutchinson, Phat L. Tran, Jawaad Sheriff, Danny Bluestein, Xiaoyi Wu, Marvin J. Slepian
Proc. ASME. SBC2013, Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments, V01AT17A027, June 26–29, 2013
Paper No: SBC2013-14780
https://doi.org/10.1115/SBC2013-14780
View Paper titled, Platelet Activity of Coaxial Electrospun Scaffolds for Applications in Cardiovascular Tissue Engineering
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Topics: Cardiovascular system, Platelets, Tissue engineering, Ethanol, Gelatin, Adhesion, Biocompatibility, Design, Drug delivery systems, Endothelial cells
Proceedings Papers

Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Coarse Grained Molecular Dynamics

Peng Zhang, Jawaad Sheriff, João S. Soares, Chao Gao, Seetha Pothapragada, Na Zhang, Yuefan Deng, Danny Bluestein
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT36A002, June 26–29, 2013
Paper No: SBC2013-14187
https://doi.org/10.1115/SBC2013-14187
View Paper titled, Multiscale Modeling of Flow Induced Thrombogenicity Using Dissipative Particle Dynamics and Coarse Grained Molecular Dynamics
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Topics: Flow (Dynamics), Molecular dynamics, Multiscale modeling, Particle dynamics, Platelets, Thrombosis, Blood, Blood flow, Erythrocytes, Fluids
Proceedings Papers

Dynamic Shear Stress Induced Platelet Activation in Blood Recirculation Devices: Implications for Thrombogenicity Minimization

Gaurav Girdhar, Jawaad Sheriff, Michalis Xenos, Yared Alemu, Thomas Claiborne, Marvin Slepian, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 231-232, June 17–21, 2009
Paper No: SBC2009-206353
https://doi.org/10.1115/SBC2009-206353
View Paper titled, Dynamic Shear Stress Induced Platelet Activation in Blood Recirculation Devices: Implications for Thrombogenicity Minimization
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Topics: Blood, Platelets, Shear stress, Flow (Dynamics), Artificial hearts, Blood flow, Bridges (Structures), Cardiovascular system, Design, Diseases
Proceedings Papers

Development and Optimization of a Novel Polymeric Prosthetic Heart Valve Using the Device Thrombogenicity Emulation (DTE) Methodology

Thomas E. Claiborne, Michalis Xenos, Jawaad Sheriff, Dinesh Peter, Yared Alemu, Yasushi Kato, Leonard Pinchuk, Shmuel Einav, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 465-466, June 20–23, 2012
Paper No: SBC2012-80186
https://doi.org/10.1115/SBC2012-80186
View Paper titled, Development and Optimization of a Novel Polymeric Prosthetic Heart Valve Using the Device Thrombogenicity Emulation (DTE) Methodology
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Topics: Heart valve prostheses, Optimization, Valves, Diseases, Biological tissues, Surgery, Artificial hearts, Biocompatibility, Patient treatment
Proceedings Papers

A Mathematical Model for Shear-Induced Platelet Activation in Response to Time Dependent Shear Stress Histories

João S. Soares, Jawaad Sheriff, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1305-1306, June 20–23, 2012
Paper No: SBC2012-80133
https://doi.org/10.1115/SBC2012-80133
View Paper titled, A Mathematical Model for Shear-Induced Platelet Activation in Response to Time Dependent Shear Stress Histories
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Topics: Platelets, Shear (Mechanics), Shear stress, Blood, Cardiovascular system, Damage, Drugs, Heart valve prostheses, Risk, Ventricular assist devices
Proceedings Papers

Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments

Jawaad Sheriff, Michalis Xenos, João S. Soares, Jolyon Jesty, Danny Bluestein
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 883-884, June 20–23, 2012
Paper No: SBC2012-80134
https://doi.org/10.1115/SBC2012-80134
View Paper titled, Evaluation of Platelet Activation Models With Dynamic Shear Stress In Vitro Experiments
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Topics: Platelets, Shear stress, Blood, Flow (Dynamics), Shear (Mechanics), Diseases, Heart failure, Heart valve prostheses, Optimization, Patient treatment
Proceedings Papers

Dynamic Numerical and Experimental Evaluation of Trileaflet Polymer Prosthetic Heart Valves

Thomas E. Claiborne, Michalis Xenos, Gaurav Girdhar, Yared Alemu, Jawaad Sheriff, Marvin Slepian, Leonard Pinchuk, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1205-1206, June 22–25, 2011
Paper No: SBC2011-53176
https://doi.org/10.1115/SBC2011-53176
View Paper titled, Dynamic Numerical and Experimental Evaluation of Trileaflet Polymer Prosthetic Heart Valves
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Topics: Heart valve prostheses, Polymers, Valves, Artificial hearts, Biological tissues, Diseases, Durability, Food and Drug Administration, Frequency-domain analysis, Hemodynamics
Proceedings Papers

Design Optimization of a Mechanical Heart Valve for Reducing Valve Thrombogenicity: A Case Study With ATS Valve

Gaurav Girdhar, Yared Alemu, Michalis Xenos, Jawaad Sheriff, Jolyon Jesty, Shmuel Einav, Danny Bluestein
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 277-278, June 16–19, 2010
Paper No: SBC2010-19309
https://doi.org/10.1115/SBC2010-19309
View Paper titled, Design Optimization of a Mechanical Heart Valve for Reducing Valve Thrombogenicity: A Case Study With ATS Valve
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Topics: Design, Heart valve prostheses, Optimization, Valves, Flow (Dynamics), Artificial hearts, Patient treatment, Physiology, Platelets, Risk
Proceedings Papers

In-Vitro Thrombogenicity Assessment of Mechanical Circulatory Support Devices and Prosthetic Heart Valves

Thomas E. Claiborne, Gaurav Girdhar, Jawaad Sheriff, Jolyon Jesty, Marvin J. Slepian, Robert Benkowski, Leonard Pinchuk, Danny Bluestein
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 115-116, June 16–19, 2010
Paper No: SBC2010-19287
https://doi.org/10.1115/SBC2010-19287
View Paper titled, In-Vitro Thrombogenicity Assessment of Mechanical Circulatory Support Devices and Prosthetic Heart Valves
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Topics: Heart valve prostheses, Platelets, Artificial hearts, Blood, Bridges (Structures), Engineering prototypes, Flow (Dynamics), Heart failure, Impellers, Patient treatment
Journal Articles

In Vitro Evaluation of a Novel Hemodynamically Optimized Trileaflet Polymeric Prosthetic Heart Valve

Thomas E. Claiborne, Jawaad Sheriff, Maximilian Kuetting, Ulrich Steinseifer, Marvin J. Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021021.
Paper No: BIO-12-1474
https://doi.org/10.1115/1.4023235
Published Online: February 7, 2013
View Article titled, In Vitro Evaluation of a Novel Hemodynamically Optimized Trileaflet Polymeric Prosthetic Heart Valve
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Topics: Biological tissues, Design, Platelets, Valves, Finite element analysis, Engineering prototypes, Hydrodynamics, Polymers, Testing, Heart valve prostheses