This paper presents the design, fabrication, and experimental validation of a novel low-cost implantable pump for the treatment of refractory ascites (RA) based on local magnetic actuation (LMA). A reciprocating positive displacement pump displaces liquid unidirectionally through magnetic coupling with a magnetic controller placed on the outside of the patient's body. The proposed solution is intuitive to use given an alignment algorithm that exploits externally placed magnetic field sensors (MFS). The implantable device has a catheter-like shape, is electronic free (no on-board battery), has low fabrication cost (<8 USD), and is able to generate a flow-rate of 3.65 L/h while effectively pumping fluids with various viscosity (1–5.5 cP). RA is commonly treated via costly paracentesis or invasive surgical placement of a transjugular portosystemic shunt (TIPS). The proposed solution can be implanted with minimally invasive techniques and can be used on a daily basis to drain a set amount of liquid, without requiring recurrent hospital visits.
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September 2019
Research-Article
Miniature Pump for Treatment of Refractory Ascites Based on Local Magnetic Actuation
Nicolo Garbin,
Nicolo Garbin
Department of Mechanical Engineering,
Vanderbilt University,
Nashville, TN 37212
e-mail: nicolo.garbin.1@vanderbilt.edu
Vanderbilt University,
Nashville, TN 37212
e-mail: nicolo.garbin.1@vanderbilt.edu
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Pietro Valdastri
Pietro Valdastri
Chair in Robotics & Autonomous Systems,
School of Electronic and Electrical Engineering,
University of Leeds,
Leeds, LS2 9JT, UK
e-mail: P.Valdastri@leeds.ac.uk
School of Electronic and Electrical Engineering,
University of Leeds,
Leeds, LS2 9JT, UK
e-mail: P.Valdastri@leeds.ac.uk
Search for other works by this author on:
Nicolo Garbin
Department of Mechanical Engineering,
Vanderbilt University,
Nashville, TN 37212
e-mail: nicolo.garbin.1@vanderbilt.edu
Vanderbilt University,
Nashville, TN 37212
e-mail: nicolo.garbin.1@vanderbilt.edu
Patrick Doyle
Byron Smith
Jesse G. Taylor
Mubashir H. Khan
Qasim Khalil
Pietro Valdastri
Chair in Robotics & Autonomous Systems,
School of Electronic and Electrical Engineering,
University of Leeds,
Leeds, LS2 9JT, UK
e-mail: P.Valdastri@leeds.ac.uk
School of Electronic and Electrical Engineering,
University of Leeds,
Leeds, LS2 9JT, UK
e-mail: P.Valdastri@leeds.ac.uk
Manuscript received September 27, 2018; final manuscript received December 19, 2018; published online July 15, 2019. Assoc. Editor: Kunal Mitra.
J. Med. Devices. Sep 2019, 13(3): 031002 (10 pages)
Published Online: July 15, 2019
Article history
Received:
September 27, 2018
Revised:
December 19, 2018
Citation
Garbin, N., Doyle, P., Smith, B., Taylor, J. G., Khan, M. H., Khalil, Q., and Valdastri, P. (July 15, 2019). "Miniature Pump for Treatment of Refractory Ascites Based on Local Magnetic Actuation." ASME. J. Med. Devices. September 2019; 13(3): 031002. https://doi.org/10.1115/1.4042460
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