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Keywords: gels
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Journal Articles
Article Type: Research Papers
J Biomech Eng. November 2010, 132(11): 111008.
Published Online: October 20, 2010
...Martin Kroon A theoretical model for the remodeling of collagen gels is proposed. The collagen fabric is modeled as a network of collagen fibers, which in turn are composed of collagen fibrils. In the model, the strengthening of collagen fabric is accomplished by fibroblasts, which continuously...
Journal Articles
Article Type: Design Innovations
J Biomech Eng. June 2010, 132(6): 065001.
Published Online: April 26, 2010
... fold. 04 10 2009 21 01 2010 02 02 2010 26 04 2010 26 04 2010 biological tissues biomechanics elasticity gels physiological models surgery vibrations wounds mechanical larynx surgical experimentation vocal fold substitute agarose The purpose...
Journal Articles
Article Type: Research Papers
J Biomech Eng. May 2010, 132(5): 051008.
Published Online: March 29, 2010
... of this technique. In this paper, we analyze experimentally the force impact of high flow microinfusion on the deformable gel matrix. To investigate these fluid structure interactions, two optical methods are reported. First, gel stresses during microinfusion were visualized through a linear polariscope. Second...
Journal Articles
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101014.
Published Online: October 13, 2009
... to describe mechanically because of the ability of the cells to remodel the matrix, including compaction at short times and synthesis and/or degradation (and cell proliferation) at longer times. The objectives of this work were to measure the equilibrium modulus of fibroblast-populated gels with different...
Journal Articles
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101016.
Published Online: October 13, 2009
...Julia Raykin; Alexander I. Rachev; Rudolph L. Gleason, Jr. Mechanical stimulation has been shown to dramatically improve mechanical and functional properties of gel-derived tissue engineered blood vessels (TEBVs). Adjusting factors such as cell source, type of extracellular matrix, cross-linking...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074520.
Published Online: July 27, 2009
...Eduardo Reátegui; Alptekin Aksan Proteins and enzymes can be encapsulated in nanoporous gels to develop novel technologies for biosensing, biocatalysis, and biosynthesis. When encapsulated, certain macromolecules retain high levels of activity and functionality and are more resistant...
Journal Articles
Article Type: Design Innovations
J Biomech Eng. March 2009, 131(3): 035001.
Published Online: December 31, 2008
.... For the construction of the gel structure, sodium alginate solution was ejected from the inkjet nozzle (SEA-Jet™, Seiko Epson Corp., Suwa, Japan) and was mixed with a substrate composed of a calcium chloride solution. In our 3D bioprinter, the nozzle head can be moved in three dimensions. Owing to the development...
Journal Articles
Article Type: Research Papers
J Biomech Eng. October 2008, 130(5): 051016.
Published Online: September 15, 2008
... behavior of the regenerated cartilaginous tissue, because these tissues need to bear various dynamic loadings in daily life. The objectives of this study were to evaluate in detail the dynamic viscoelastic responses of chondrocyte-seeded agarose gel cultures in compression and torsion (shear...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. December 2007, 129(6): 919–923.
Published Online: April 24, 2007
... constructs respond to in vitro mechanical stimulation. Although one study showed that stimulating mesenchymal stem cell (MSC)–collagen sponge constructs significantly increased construct linear stiffness and repair biomechanics, a second study showed no such effect when a collagen gel replaced the sponge...
Journal Articles
Article Type: Research Papers
J Biomech Eng. December 2007, 129(6): 848–854.
Published Online: March 13, 2007
... their stiffness and modulus in culture and tendon repair biomechanics 12 weeks after surgical implantation. Using six female adult New Zealand White rabbits, autogenous tissue engineered constructs were created by seeding mesenchymal stem cells ( 0.1 × 10 6 cells ∕ ml ) in collagen gel ( 2.6 mg ∕ ml...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. October 2007, 129(5): 642–650.
Published Online: February 15, 2007
... the tissue structures and their mechanical behavior. We used a novel collagen gel system to test the hypothesis that collagen fiber alignment is the primary mechanism for the mechanical anisotropy we have reported in structurally anisotropic gels. Loading constraints applied during culture were used...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. August 2007, 129(4): 503–510.
Published Online: November 20, 2006
... represented as a hydrated gel surrounded by a semi-permeable membrane, with the gel and membrane potentially exhibiting different properties. To help assess whether this more elaborate model of the cell is justified, this study investigates the response of spherical gels to osmotic loading, both from...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. June 2007, 129(3): 430–440.
Published Online: November 15, 2006
... compression data were obtained from testing polyvinyl alcohol gels of known composition. Local elastic properties of tissue-engineered cartilage were also measured by the AFM. All AFM data sets were processed using customized software based on the algorithm, and the extracted values of Young’s modulus were...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. October 2005, 127(5): 742–750.
Published Online: May 19, 2005
...Stavros Thomopoulos; Gregory M. Fomovsky; Jeffrey W. Holmes An in vitro model system was developed to study structure-function relationships and the development of structural and mechanical anisotropy in collagenous tissues. Fibroblast-populated collagen gels were constrained either biaxially...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. February 2005, 127(1): 148–157.
Published Online: March 8, 2005
... set of material parameters. The material parameters which best fit the FEM predicted displacements to the displacements reconstructed from the tagged images were found by nonlinear optimization. The equipment and method were validated using inflation of a deformable silicon gel phantom in the shape...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. June 2005, 127(3): 536–540.
Published Online: January 31, 2005
... significantly change the compressive stiffness of the human lumbar IVD. Implant geometrical variations were more effective than those of implant modulus variations in the range examined. 27 09 2003 27 11 2004 31 01 2005 bone neurophysiology orthopaedics gels biomedical materials...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. April 2005, 127(2): 220–228.
Published Online: November 18, 2004
...Jeanie L. Drury; Tanyarut Boontheekul; David J. Mooney Peptide modification of hydrogel-forming materials is being widely explored as a means to regulate the phenotype of cells immobilized within the gels. Alternatively, we hypothesized that the adhesive interactions between cells and peptides...
Journal Articles
Article Type: Errata
J Biomech Eng. August 2004, 126(4): 541.
Published Online: September 27, 2004
...Robert L. Mauck,; Clark T. Hung, and; Gerard A. Ateshian 27 09 2004 bone tissue engineering biotransport modelling biomechanics biorheology porous materials gels permeability biodiffusion biological tissues convection biomedical materials Typesetting corrections...
Journal Articles
Article Type: Errata
J Biomech Eng. June 2004, 126(3): 392.
Published Online: June 24, 2004
...Robert L. Mauck,; Clark T. Hung, and; Gerard A. Ateshian 24 06 2004 gels permeability biodiffusion biological tissues biomechanics convection porous materials biomedical materials Typesetting corrections for Eqs. ( 32 ), ( 48 ), and ( 49 ): (32) u r r , 0...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. April 2004, 126(2): 152–166.
Published Online: May 4, 2004
...Preethi L. Chandran; Victor H. Barocas Background: Collagen gels are important as platforms for in vitro study of cell behavior and as prototypical bioartificial tissues, but their mechanical behavior, particularly on the microscopic scale, is still poorly understood. Method of Approach: Collagen...