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Keywords: extracellular matrix
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Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2024, 146(7): 071009.
Paper No: BIO-23-1411
Published Online: April 17, 2024
... strain best maintains native physiology while promoting extracellular matrix (ECM) turnover for both age groups. However, aged tendons display fewer strain-dependent changes, suggesting a reduced ability to adapt to altered levels of mechanical loading. This work has a significant impact on understanding...
Includes: Supplementary data
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021011.
Paper No: BIO-13-1492
Published Online: February 5, 2014
... February 5, 2014. Editor: Victor H. Barocas. 16 10 2013 28 12 2013 09 01 2014 Tumor progression depends critically upon the interactions between the tumor cells and their microenvironment. The tumor microenvironment is heterogeneous and dynamic; it consists of extracellular matrix...
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021001.
Paper No: BIO-13-1503
Published Online: February 5, 2014
... deformation, and live two-photon microscopy was used to obtain insight into the dynamic mechanical interaction between angiogenic neovessels and the extracellular matrix. In these studies, we characterized how angiogenic neovessels remodel the extracellular matrix (ECM) and how properties of the matrix...
Includes: Multimedia, Supplementary data
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2013, 135(9): 091001.
Paper No: BIO-12-1240
Published Online: July 10, 2013
.... References [1] Berthiaume , F. , Moghe , P. V. , Toner , M. , and Yarmush , M. L. , 1996 , “ Effect of Extracellular Matrix Topology on Cell Structure, Function, and Physiological Responsiveness: Hepatocytes Cultured in a Sandwich Configuration ,” FASEB J. , 10 , pp. 1471 – 1484...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Design Innovations
J Biomech Eng. September 2011, 133(9): 095001.
Published Online: October 11, 2011
... neurophysiology proteins stress-strain relations microstructure extracellular matrix two-photon sclera glaucoma multiphoton According to the World Health Organization, glaucoma is estimated to affect 80 × 10 6 people by 2020 worldwide, making it the second leading cause of blindness [( 1...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2009, 131(3): 031004.
Published Online: January 5, 2009
...Blayne A. Roeder; Klod Kokini; Sherry L. Voytik-Harbin The next generation of medical devices and engineered tissues will require development of scaffolds that mimic the structural and functional properties of the extracellular matrix (ECM) component of tissues. Unfortunately, little is known...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2007, 129(6): 880–889.
Published Online: April 19, 2007
... quantified. Local collagen fiber alignment in the same valves was also quantified using small angle light scattering. A tissue-level finite element (FE) model of an AVIC embedded in the AV extracellular matrix was also used explore the relation between AV tissue- and cellular-level deformations. Results...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2002, 124(6): 724–733.
Published Online: December 27, 2002
... and that changes in extracellular matrix composition and matrix gene expression in the presence of RA/AA treatment may play an important role in the development of said mechanical properties. Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING . Manuscript...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. April 2002, 124(2): 214–222.
Published Online: March 29, 2002
...Blayne A. Roeder; Klod Kokini; Jennifer E. Sturgis; J. Paul Robinson; Sherry L. Voytik-Harbin The importance and priority of specific micro-structural and mechanical design parameters must be established to effectively engineer scaffolds (biomaterials) that mimic the extracellular matrix (ECM...