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Keywords: computational fluid dynamics
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Journal Articles
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051011.
Paper No: BIO-20-1056
Published Online: March 8, 2021
... is unclear. Idealized LM coronary arteries with 34 different intermediate stenoses were created and categorized (Medina) as single and multiple lesion groups. Computational fluid dynamics modeling was performed with physiologic boundary conditions using an open-source software ( simvascular 1 ) to solve...
Journal Articles
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051003.
Paper No: BIO-20-1201
Published Online: March 4, 2021
... fluid (CSF) near the foramen magnum (FM). We used computational fluid dynamics (CFD) to compute patient-specific resistance to CSF motion in the spinal canal for CMI patients to determine its accuracy in predicting CAH. Fifty-one symptomatic CMI patients with cerebellar tonsillar position (CTP) ≥ 5 mm...
Journal Articles
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031013.
Paper No: BIO-20-1107
Published Online: January 22, 2021
... or different regarding their impacts on coronary hemodynamics. The purpose of this study was to compare the hemodynamic effects of coronary stenosis and MB using experimental and computational fluid dynamics (CFD) approaches. For CFD modeling, three MB patients with different levels of lumen obstruction, mild...
Includes: Supplementary data
Journal Articles
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031009.
Paper No: BIO-20-1247
Published Online: December 10, 2020
... coiling (SAC). Therefore, we performed computational fluid dynamics (CFD) analysis of the blood flow in four bifurcation aneurysms focusing on the stent healing period found in SAC as a two-step maneuver. Our results show that by changing the local vasculature, the intra-aneurysmal hemodynamics changes...
Journal Articles
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011009.
Paper No: BIO-19-1304
Published Online: October 8, 2020
... by computational fluid dynamics (CFD) simulations has become conventional, convergence of hemolysis calculations is also essential. In this paper, convergence of the power-law hemolysis model is compared for simple flows, including pathlines with exponentially increasing and decreasing stress, in gradually...
Journal Articles
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011002.
Paper No: BIO-19-1356
Published Online: September 30, 2020
... and personalized dosimetry. Computational fluid dynamics (CFD) simulations were performed in a 3D hepatic arterial tree model segmented from cone-beam CT angiographic data obtained from a patient with hepatocellular carcinoma (HCC). The microsphere trajectories were predicted from the velocity field. 90 Y dose...
Includes: Supplementary data
Journal Articles
Article Type: Research-Article
J Biomech Eng. September 2020, 142(9): 091002.
Paper No: BIO-18-1496
Published Online: April 13, 2020
... in computational fluid dynamics (CFD) simulations of veins with CVCs. e-mail:  Lqpeng0214@126.com e-mail:  tinghuizh@scu.edu.cn 1 Min-Hyuk Park and Yue Qiu contribute equally to this work. 15 11 2018 30 01 2020 13 04 2020 central venous catheter computational fluid...
Journal Articles
Article Type: Research-Article
J Biomech Eng. January 2020, 142(1): 011010.
Paper No: BIO-18-1404
Published Online: October 1, 2019
... of the metamodel and in vivo measured pressure drops, the mean bias (−0.2 ± 13.7 mmHg) and the coefficient of determination (R 2 = 0.80) were as good as of the original 2D computational fluid dynamics (CFD) model. UQ results of the 2D and metamodel were comparable. Estimation of the uncertainty interval using...
Journal Articles
Article Type: Research-Article
J Biomech Eng. November 2019, 141(11): 111002.
Paper No: BIO-18-1204
Published Online: July 30, 2019
... 2018 20 05 2019 aortic dissection thoracic endovascular aortic repair left subclavian artery coverage computational fluid dynamics fluid–structure interaction Windkessel model Aortic dissection is a lethal cardiovascular disease, which is a serious hazard to human health...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. October 2019, 141(10): 104501.
Paper No: BIO-18-1280
Published Online: July 15, 2019
... in a patient-specific aorta to investigate mixing and dispersion of contrast in the aortic arch (AA) and to compare the TDCs in the coronary ostium and the descending aorta. Here, we examine the validity of the use of TDC in the descending aorta as a surrogate for the AIF. Computational fluid dynamics (CFD...
Journal Articles
Article Type: Research-Article
J Biomech Eng. October 2019, 141(10): 101002.
Paper No: BIO-18-1058
Published Online: July 11, 2019
... bileaflet mechanical valves computational fluid dynamics fluid–structure interaction Prosthetic valve thrombosis (PVT) is a rare and serious complication that affects prosthetic heart valves (PHVs). PVT consists in a thrombus or pannus formation that may hinder the leaflet movement, increasing...
Journal Articles
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 061001.
Paper No: BIO-17-1599
Published Online: April 22, 2019
...Digvijay S. Rawat; Mathieu Pourquie; Christian Poelma Computational fluid dynamics (CFD) is a powerful method to investigate aneurysms. The primary focus of most investigations has been to compute various hemodynamic parameters to assess the risk posed by an aneurysm. Despite the occurrence...
Journal Articles
Article Type: Research-Article
J Biomech Eng. March 2015, 137(3): 031002.
Paper No: BIO-13-1410
Published Online: March 1, 2015
...% TE in the pulsatile simulations, warranting further studies to improve the mathematical model and experimental validation. computational fluid dynamics blood flow drug targeting nanoparticles controlled release Targeted drug delivery is a technique of delivering drugs to specific...
Journal Articles
Article Type: Research-Article
J Biomech Eng. August 2014, 136(8): 081003.
Paper No: BIO-13-1517
Published Online: June 2, 2014
... were higher in the retroaortic IVC than in the left-sided IVC (144 mm 2 , 0.47 N, and 1.49 mm versus 68 mm 2 , 0.22 N, and 1.01 mm, respectively). Hemodynamics were simulated using computational fluid dynamics (CFD), with four cases for each patient-specific vein: (1) IVC only, (2) IVC with a placed...
Journal Articles
Article Type: Research-Article
J Biomech Eng. July 2014, 136(7): 071012.
Paper No: BIO-13-1526
Published Online: May 23, 2014
... on, the exposed thrombus surfaces are calculated using computational fluid dynamics (CFD). Both the mean and maximum WSS on the exposed thrombus surfaces are much more dependent on thrombus topography than thrombus size, and the best predictors for asymptotic thrombus length and volume are the reattachment length...
Journal Articles
Article Type: Research-Article
J Biomech Eng. June 2014, 136(6): 061006.
Paper No: BIO-13-1266
Published Online: May 6, 2014
.... H. , Bendok , B. R. , Hanel , R. A. , Guterman , L. R. , and Hopkins , L. N. , 2004 , “ Effects of Arterial Geometry on Aneurysm Growth: Three-Dimensional Computational Fluid Dynamics Study ,” J. Neurosurg. , 101 ( 4 ), pp. 676 – 681 . 10.3171/jns.2004.101.4.0676 [12...
Journal Articles
Article Type: Research-Article
J Biomech Eng. April 2014, 136(4): 041003.
Paper No: BIO-13-1247
Published Online: March 24, 2014
...; accepted manuscript posted November 27, 2013; published online March 24, 2014. Assoc. Editor: Dalin Tang. 30 05 2013 21 11 2013 27 11 2013 Computational fluid dynamics (CFD) opens up multiple opportunities to investigate the hemodynamics of the human vascular system. However, due...
Journal Articles
Article Type: Research-Article
J Biomech Eng. December 2013, 135(12): 121009.
Paper No: BIO-13-1014
Published Online: November 6, 2013
... online November 6, 2013. Assoc. Editor: Dalin Tang. 11 01 2013 10 10 2013 19 10 2013 The goal of this study is to develop a computational fluid dynamics (CFD) modeling approach to better estimate the blood flow dynamics in the bundles of the hollow fiber membrane based medical...
Journal Articles
Article Type: Research-Article
J Biomech Eng. December 2013, 135(12): 121002.
Paper No: BIO-13-1262
Published Online: October 4, 2013
... was to establish a computational fluid dynamics model to investigate the effect of cyclic motion (i.e., bending and stretching) on coronary blood flow. The three-dimensional (3D) geometry of a 50-mm section of the left anterior descending artery (normal or with a 60% stenosis) was constructed based on anatomical...
Journal Articles
Article Type: Research-Article
J Biomech Eng. May 2013, 135(5): 051005.
Paper No: BIO-12-1570
Published Online: April 24, 2013
... in concentrations that are physiologically counterintuitive. Understanding the transport mechanisms and flow regimes in the lymphatic vasculature could help in the development of therapeutics to treat lymphatic disorders. nitric oxide computational fluid dynamics mass transport lymphatic...