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Journal Articles

The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers

Thao (Vicky) Nguyen, C. Ross Ethier
Journal: Journal of Biomechanical Engineering
Article Type: Editorial
J Biomech Eng. August 2023, 145(8): 080202.
Paper No: BIO-23-1214
https://doi.org/10.1115/1.4062744
Published Online: June 28, 2023
View Article titled, The 2021 Richard Skalak Award and the 2021 Editors' Choice Papers
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Topics: Deformation, Fluids, Osteoarthritis, Bioengineering, Students, Algorithms, Arches, Armor, Bearings, Biological tissues
Journal Articles

An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation

Gozde Basara, Gokhan Bahcecioglu, Xiang Ren, Pinar Zorlutuna
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2023, 145(8): 081004.
Paper No: BIO-22-1304
https://doi.org/10.1115/1.4062736
Published Online: June 21, 2023
View Article titled, An Experimental and Numerical Investigation of Cardiac Tissue-Patch Interrelation
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Topics: Biological tissues, Computer simulation, Deformation, Gelatin, Proteins, Relaxation (Physics), Synchronization, Transients (Dynamics), Hydrogels
Includes: Supplementary data
Journal Articles

Dynein Dysfunction Prevents Maintenance of High Concentrations of Slow Axonal Transport Cargos at the Axon Terminal: A Computational Study

Ivan A. Kuznetsov, Andrey V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. July 2023, 145(7): 071001.
Paper No: BIO-22-1199
https://doi.org/10.1115/1.4056915
Published Online: March 28, 2023
View Article titled, Dynein Dysfunction Prevents Maintenance of High Concentrations of Slow Axonal Transport Cargos at the Axon Terminal: A Computational Study
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Topics: Diffusion (Physics), Maintenance, Motors, Proteins, Engines, Boundary-value problems, Modeling
Includes: Supplementary data
Journal Articles

Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning

Ali Behrangzade, Bruce R. Simon, William R. Wagner, Jonathan P. Vande Geest
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021002.
Paper No: BIO-22-1025
https://doi.org/10.1115/1.4055563
Published Online: October 6, 2022
View Article titled, Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
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Topics: Aorta, Fluids, Optimization, Permeability, Simulation, Flow (Dynamics), Thrombosis, Geometry, Finite element analysis, Platelets
Journal Articles

Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms

Christian J. Mandrycky, Ashley N. Abel, Samuel Levy, Laurel M. Marsh, Fanette Chassagne, Venkat K. Chivukula, Sari E. Barczay, Cory M. Kelly, Louis J. Kim, Alberto Aliseda, Michael R. Levitt, Ying Zheng
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011001.
Paper No: BIO-21-1298
https://doi.org/10.1115/1.4054981
Published Online: August 19, 2022
View Article titled, Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms
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Topics: Aneurysms, Computational fluid dynamics, Endothelial cells, Flow (Dynamics), Hemodynamics, Proteins, Vessels, Polarization (Electricity), Polarization (Light), Polarization (Waves)
Includes: Supplementary data
Journal Articles

Effect of Slp4-a on Membrane Bending During Prefusion of Vesicles in Blood-Brain Barrier

Quyen Van Dinh, Jin Liu, Prashanta Dutta
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011006.
Paper No: BIO-22-1077
https://doi.org/10.1115/1.4054985
Published Online: August 19, 2022
View Article titled, Effect of Slp4-a on Membrane Bending During Prefusion of Vesicles in Blood-Brain Barrier
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Topics: Brain, Ions, Membranes, Proteins, Simulation, Blood, Atoms
Includes: Supplementary data
Journal Articles

Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus

Gabi Schwartz, Andy Morejon, Thomas M. Best, Alicia R. Jackson, Francesco Travascio
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111010.
Paper No: BIO-22-1084
https://doi.org/10.1115/1.4054931
Published Online: July 18, 2022
View Article titled, Strain-Dependent Diffusivity of Small and Large Molecules in Meniscus
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Topics: Anisotropy, Biological tissues, Compression, Diffusion (Physics), Fibers, Fluorescence, Proteins
Journal Articles

The Elephant in the Cell: Nuclear Mechanics and Mechanobiology

Michelle L. Jones, Kris Noel Dahl, Tanmay P. Lele, Daniel E. Conway, Vivek Shenoy, Soham Ghosh, Spencer E. Szczesny
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. August 2022, 144(8): 080802.
Paper No: BIO-21-1401
https://doi.org/10.1115/1.4053797
Published Online: March 11, 2022
View Article titled, The Elephant in the Cell: Nuclear Mechanics and Mechanobiology
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Topics: Biological tissues, Computer simulation, Deformation, Mechanical properties, Mechanobiology, Modeling, Proteins, Shapes, Tension, Stress
Journal Articles

Erratum: “Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia” [ASME J. Biomech. Eng., 2021, 143(3), p. 031004; DOI: 10.1115/1.4053610 ]

Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Harifidy Randrianalisoa, Zhengpeng Qin
Journal: Journal of Biomechanical Engineering
Article Type: Errata
J Biomech Eng. August 2022, 144(8): 087001.
Paper No: BIO-21-1364
https://doi.org/10.1115/1.4053610
Published Online: February 21, 2022
View Article titled, Erratum: “Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia” [ASME J. Biomech. Eng., 2021, 143(3), p. 031004; DOI: 10.1115/1.4053610 ]
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Topics: Proteins
Journal Articles

The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review

Lainie E. Eisner, Ryan Rosario, Nelly Andarawis-Puri, Ellen M. Arruda
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. May 2022, 144(5): 050801.
Paper No: BIO-21-1296
https://doi.org/10.1115/1.4053086
Published Online: December 20, 2021
View Article titled, The Role of the Non-Collagenous Extracellular Matrix in Tendon and Ligament Mechanical Behavior: A Review
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Topics: Biological tissues, Fibers, Mechanical behavior, Tendons, Stress, Proteins
Journal Articles

Influence of Hydroxyproline on Mechanical Behavior of Collagen Mimetic Proteins Under Fraying Deformation—Molecular Dynamics Investigations

Atul Rawal, Kristen L. Rhinehardt, Ram V. Mohan, Max Pendse
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2021, 143(8): 081009.
Paper No: BIO-20-1494
https://doi.org/10.1115/1.4050648
Published Online: May 4, 2021
View Article titled, Influence of Hydroxyproline on Mechanical Behavior of Collagen Mimetic Proteins Under Fraying Deformation—Molecular Dynamics Investigations
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Topics: Chain, Deformation, Proteins, Separation (Technology), Simulation, Mechanical properties, Molecular dynamics, Binding energy
Includes: Supplementary data
Journal Articles

The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction

Mostafa Mahmoudi, Ali Farghadan, Daniel R. McConnell, Alex J. Barker, Jolanda J. Wentzel, Matthew J. Budoff, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. April 2021, 143(4): 041002.
Paper No: BIO-20-1283
https://doi.org/10.1115/1.4049026
Published Online: December 14, 2020
View Article titled, The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
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Topics: Atherosclerosis, Coronary arteries, Oxygen, Proteins, Shear stress, Density, Endothelial cells, Permeability, Diseases, Computational fluid dynamics
Journal Articles

Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia

Peiyuan Kang, Chen Xie, Oumar Fall, Jaona Randrianalisoa, Zhenpeng Qin
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2021, 143(3): 031004.
Paper No: BIO-20-1113
https://doi.org/10.1115/1.4049017
Published Online: December 10, 2020
View Article titled, Computational Investigation of Protein Photoinactivation by Molecular Hyperthermia
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Topics: Heating, Nanoparticles, Proteins, Temperature, Materials properties, Lasers, Shapes
Includes: Supplementary data
Journal Articles

Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse

Mitchel C. Whittal, Sara Molladavoodi, Derek P. Zwambag, Magali Millecamps, Laura S. Stone, Diane E. Gregory
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. February 2021, 143(2): 024501.
Paper No: BIO-20-1065
https://doi.org/10.1115/1.4047995
Published Online: October 8, 2020
View Article titled, Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse
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Topics: Intervertebral discs, Lumbar spine, Stiffness, Mechanical testing, Proteins, Mechanical properties
Journal Articles

Nonlinear Elastic and Inelastic Properties of Cells

Wonyeong Jung, Jing Li, Ovijit Chaudhuri, Taeyoon Kim
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100806.
Paper No: BIO-19-1549
https://doi.org/10.1115/1.4046863
Published Online: August 31, 2020
View Article titled, Nonlinear Elastic and Inelastic Properties of Cells
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Topics: Atomic force microscopy, Computer simulation, Deformation, Mechanical properties, Rheology, Stress, Viscoelasticity, Relaxation (Physics), Fibroblasts, Membranes
Journal Articles

Probing Flow-Induced Biomolecular Interactions With Micro-Extensional Rheology: Tau Protein Aggregation

H. Hosseini, A. Rangchian, M. L. Prins, C. C. Giza, J. W. Ruberti, H. P. Kavehpour
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. March 2020, 142(3): 034501.
Paper No: BIO-19-1516
https://doi.org/10.1115/1.4046330
Published Online: February 28, 2020
View Article titled, Probing Flow-Induced Biomolecular Interactions With Micro-Extensional Rheology: Tau Protein Aggregation
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Topics: Flow (Dynamics), Proteins, Rheology, Relaxation (Physics), Shear (Mechanics)
Includes: Supplementary data
Journal Articles

A Dynamic Escape Problem of Molecular Motors

Dean Culver, Bryan Glaz, Samuel Stanton
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2020, 142(5): 051004.
Paper No: BIO-18-1527
https://doi.org/10.1115/1.4044580
Published Online: January 20, 2020
View Article titled, A Dynamic Escape Problem of Molecular Motors
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Topics: Bridges (Structures), Dimensions, Molecular motors, Motors, Muscle, Particulate matter, Potential energy, Design, Proteins, Dynamics (Mechanics)
Journal Articles

Cardiac Protective Engineering

Shu Q. Liu
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. September 2019, 141(9): 090801.
Paper No: BIO-19-1058
https://doi.org/10.1115/1.4043434
Published Online: August 2, 2019
View Article titled, Cardiac Protective Engineering
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Topics: Proteins, Wounds, Biological tissues, Myocardium, Liver
Journal Articles

Concentration-Dependent Effects of Fibroblast-Like Synoviocytes on Collagen Gel Multiscale Biomechanics and Neuronal Signaling: Implications for Modeling Human Ligamentous Tissues

Meagan E. Ita, Beth A. Winkelstein
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091013.
Paper No: BIO-19-1119
https://doi.org/10.1115/1.4044051
Published Online: August 2, 2019
View Article titled, Concentration-Dependent Effects of Fibroblast-Like Synoviocytes on Collagen Gel Multiscale Biomechanics and Neuronal Signaling: Implications for Modeling Human Ligamentous Tissues
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Topics: Biological tissues, Biomechanics, Failure, Fibers, Fibroblasts, Physiology, Proteins, Stress, Tension, Stiffness
Journal Articles

Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis

Shan Sun, Djanybek Adyshev, Steven Dudek, Amit Paul, Andrew McColloch, Michael Cho
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2019, 141(8): 081005.
Paper No: BIO-18-1375
https://doi.org/10.1115/1.4043253
Published Online: May 6, 2019
View Article titled, Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis
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Topics: Atomic force microscopy, Biomechanics, Membranes, Proteins, Stem cells, Cellular mechanics, Stiffness, Elasticity