The photoselective vaporization of prostate (PVP) green light (532 nm) laser is increasingly being used as an alternative to the transurethral resection of prostate (TURP) for treatment of benign prostatic hyperplasia (BPH) in older patients and those who are poor surgical candidates. In order to achieve the goals of increased tissue removal volume (i.e., “ablation” in the engineering sense) and reduced collateral thermal damage during the PVP green light treatment, a two dimensional computational model for laser tissue ablation based on available parameters in the literature has been developed and compared to experiments. The model is based on the control volume finite difference and the enthalpy method with a mechanistically defined energy necessary to ablate (i.e., physically remove) a volume of tissue (i.e., energy of ablation Eab). The model was able to capture the general trends experimentally observed in terms of ablation and coagulation areas, their ratio (therapeutic index (TI)), and the ablation rate (AR) (mm3/s). The model and experiment were in good agreement at a smaller working distance (WD) (distance from the tissue in mm) and a larger scanning speed (SS) (laser scan speed in mm/s). However, the model and experiment deviated somewhat with a larger WD and a smaller SS; this is most likely due to optical shielding and heat diffusion in the laser scanning direction, which are neglected in the model. This model is a useful first step in the mechanistic prediction of PVP based BPH laser tissue ablation. Future modeling efforts should focus on optical shielding, heat diffusion in the laser scanning direction (i.e., including 3D effects), convective heat losses at the tissue boundary, and the dynamic optical, thermal, and coagulation properties of BPH tissue.
Skip Nav Destination
e-mail: bischof@umn.edu
Article navigation
October 2012
Research Papers
Potassium Titanyl Phosphate Laser Tissue Ablation: Development and Experimental Validation of a New Numerical Model
Hossam Elkhalil,
Hossam Elkhalil
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455; Department of Biomedical Engineering, Jordan University of Science and Technology, Irbid, 21110, Jordan
Search for other works by this author on:
Taner Akkin,
Taner Akkin
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455
Search for other works by this author on:
John Pearce,
John Pearce
Department of Electrical and Computer Engineering, University of Texas
, Austin, TX 78712
Search for other works by this author on:
John Bischof
e-mail: bischof@umn.edu
John Bischof
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455; Department of Mechanical Engineering and Urologic Surgery, University of Minnesota, Minneapolis, MN 55455
Search for other works by this author on:
Hossam Elkhalil
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455; Department of Biomedical Engineering, Jordan University of Science and Technology, Irbid, 21110, Jordan
Taner Akkin
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455
John Pearce
Department of Electrical and Computer Engineering, University of Texas
, Austin, TX 78712
John Bischof
Department of Biomedical Engineering, University of Minnesota
, Minneapolis, MN 55455; Department of Mechanical Engineering and Urologic Surgery, University of Minnesota, Minneapolis, MN 55455e-mail: bischof@umn.edu
J Biomech Eng. Oct 2012, 134(10): 101002 (13 pages)
Published Online: October 1, 2012
Article history
Received:
February 17, 2012
Revised:
August 3, 2012
Posted:
September 27, 2012
Published:
October 1, 2012
Online:
October 1, 2012
Citation
Elkhalil, H., Akkin, T., Pearce, J., and Bischof, J. (October 1, 2012). "Potassium Titanyl Phosphate Laser Tissue Ablation: Development and Experimental Validation of a New Numerical Model." ASME. J Biomech Eng. October 2012; 134(10): 101002. https://doi.org/10.1115/1.4007452
Download citation file:
Get Email Alerts
Cited By
Related Articles
Transient Elastic and Viscoelastic Thermal Stresses During Laser Drilling of Ceramics
J. Heat Transfer (November,1998)
Nanosecond Time-Resolved Measurements of Transient Hole Opening During Laser Micromachining of an Aluminum Film
J. Heat Transfer (September,2013)
Non-Equilibrium Phase Change in Metal Induced by Nanosecond Pulsed Laser Irradiation
J. Heat Transfer (April,2002)
Temperature-Dependent Absorptances of Ceramics for Nd:YAG and CO 2 Laser Processing Applications
J. Heat Transfer (May,1998)
Related Proceedings Papers
Related Chapters
A Radio Frequency Antenna for Tumor Ablation
Electromagnetic Induction Imaging: Theory and Biomedical Applications
Use of Ablation Materials As Heat Shield to Protect Spacecrafts Entering Earth’s Atmosphere From Incoming Excessive Heat Loads
Case Studies in Transient Heat Transfer With Sensitivities to Governing Variables
Novel and Efficient Mathematical and Computational Methods for the Analysis and Architecting of Ultralight Cellular Materials and their Macrostructural Responses
Advances in Computers and Information in Engineering Research, Volume 2