Cardiac imaging using magnetic resonance requires a gating signal in order to compensate for motion. Human patients are routinely scanned using an electrocardiogram (ECG) as a gating signal during imaging. However, we found that in sheep the ECG is not a reliable method for gating. We developed a software based method that allowed us to use the left ventricular pressure (LVP) as a reliable gating signal. By taking the time derivative of the LVP (dP/dt), we were able to start imaging at both end-diastole for systolic phase images, and end-systole for diastolic phase images. We also used MR tissue tagging to calculate 3D strain information during diastole. Using the LVP in combination with our digital circuit provided a reliable and time efficient method for ovine cardiac imaging. Unlike the ECG signal the left ventricular pressure was a clean signal and allowed for accurate, nondelay based triggering during systole and diastole.
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San Francisco, CA 94143
San Francisco, CA 94121
San Francisco, CA 94143;
San Francisco, CA 94121
San Francisco, CA 94143;
San Francisco, CA 94121
San Francisco, CA 94143;
San Francisco, CA 94121
San Francisco, CA 94143;
San Francisco, CA 94121
e-mail: mark.ratcliffe@med.va.gov
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March 2013
Technical Briefs
Left Ventricular Pressure Gating in Ovine Cardiac Studies: A Software-Based Method
Gabriel Acevedo-Bolton,
San Francisco, CA 94143
Gabriel Acevedo-Bolton
Department of Radiology
,University of California
,San Francisco, CA 94143
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Zhihong Zhang,
San Francisco, CA 94121
Zhihong Zhang
Department of Surgery
,Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
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Arthur W. Wallace,
San Francisco, CA 94143;
San Francisco, CA 94121
Arthur W. Wallace
Department of Anesthesia
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
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Julius M. Guccione,
San Francisco, CA 94143;
San Francisco, CA 94121
Julius M. Guccione
Department of Surgery
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
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David A. Saloner,
San Francisco, CA 94143;
San Francisco, CA 94121
David A. Saloner
Departments of Radiology
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
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Mark B. Ratcliffe
San Francisco, CA 94143;
San Francisco, CA 94121
e-mail: mark.ratcliffe@med.va.gov
Mark B. Ratcliffe
1
Department of Surgery
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
e-mail: mark.ratcliffe@med.va.gov
1Corresponding author.
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Gabriel Acevedo-Bolton
Department of Radiology
,University of California
,San Francisco, CA 94143
Zhihong Zhang
Department of Surgery
,Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
Arthur W. Wallace
Department of Anesthesia
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
Julius M. Guccione
Department of Surgery
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
David A. Saloner
Departments of Radiology
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
Mark B. Ratcliffe
Department of Surgery
,University of California
,San Francisco, CA 94143;
Department of Veterans Affairs Medical Center
,San Francisco, CA 94121
e-mail: mark.ratcliffe@med.va.gov
1Corresponding author.
Contributed by the Bioengineering Division of ASME for publication in the Journal of Biomechanical Engineering. Manuscript received July 3, 2012; final manuscript received December 14, 2012; accepted manuscript posted January 10, 2013; published online February 11, 2013. Assoc. Editor: Ender A. Finol.
J Biomech Eng. Mar 2013, 135(3): 034502 (5 pages)
Published Online: February 11, 2013
Article history
Received:
July 3, 2012
Revision Received:
December 14, 2012
Accepted:
January 10, 2013
Citation
Acevedo-Bolton, G., Suzuki, T., Malhotra, D., Zhang, Z., Wallace, A. W., Guccione, J. M., Saloner, D. A., and Ratcliffe, M. B. (February 11, 2013). "Left Ventricular Pressure Gating in Ovine Cardiac Studies: A Software-Based Method." ASME. J Biomech Eng. March 2013; 135(3): 034502. https://doi.org/10.1115/1.4023370
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