Blood flow velocity was measured in the dog aorta distal to mechanically induced constrictions of various degrees of severity employing an 8-MHz pulsed Doppler ultrasound velocimeter and a phase-lock loop frequency tracking method for extracting velocity from the Doppler quadrature signals. The data were analyzed to construct ensemble average velocity waveforms and random velocity disturbances. In any individual animal the effect of increasing the degree of stenosis beyond approximately 25 percent area reduction was to produce increasing levels of random velocity disturbance. However, variability among animals was such that the sensitivity of random behavior to the degree of stenosis was degraded to the point that it appears difficult to employ Doppler ultrasound measurements of random disturbances to discriminate among stenoses with area reductions less than approximately 75 percent. On the other hand, coherent vortex structures in velocity waveforms consistently occurred distal to mild constrictions (25–50 percent area reduction). Comparison of the phase-lock loop Doppler ultrasound data with simultaneous measurements using invasive hot-film anemometry, which possesses excellent frequency response, demonstrates that the ultrasound method can reliably detect those flow phenomena in such cases. Thus, the identification of coherent, rather than random, flow disturbances may offer improved diagnostic capability for noninvasively detecting arteriosclerotic plaques at relatively early stages of development.
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August 1986
Research Papers
Poststenotic Flow Disturbance in the Dog Aorta as Measured With Pulsed Doppler Ultrasound
N. Talukder,
N. Talukder
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
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J. T. Fulenwider,
J. T. Fulenwider
Veterans Administration Medical Center, Altanta, Ga. 30033
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R. F. Mabon,
R. F. Mabon
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
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D. P. Giddens
D. P. Giddens
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
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N. Talukder
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
J. T. Fulenwider
Veterans Administration Medical Center, Altanta, Ga. 30033
R. F. Mabon
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
D. P. Giddens
School of Aerospace Engineering, Georgia Institute of Technology, Atlanta, Ga. 30332
J Biomech Eng. Aug 1986, 108(3): 259-265 (7 pages)
Published Online: August 1, 1986
Article history
Received:
December 9, 1985
Revised:
April 7, 1986
Online:
June 12, 2009
Citation
Talukder, N., Fulenwider, J. T., Mabon, R. F., and Giddens, D. P. (August 1, 1986). "Poststenotic Flow Disturbance in the Dog Aorta as Measured With Pulsed Doppler Ultrasound." ASME. J Biomech Eng. August 1986; 108(3): 259–265. https://doi.org/10.1115/1.3138612
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