The nonlinear two-layer arterial wall model introduced by von Maltzahn, et al. [11] is subjected to a rigorous parameter sensitivity and range of validity analysis. The model is based on the assumption that in large muscular conduit arteries the two mechanically significant layers are media and adventitia. Using curve-fitting techniques, the media is determined to be isotropic and the adventitia to be anisotropic. As a result of the range of validity analysis, the polynomial relationship for the energy density function of the media is changed to an exponential relationship. This leads to new coefficients for the polynomial of the adventitia. All coefficients have specific mechanical meanings. The parameter sensitivity analysis demonstrates convincingly that all model parameters are significantly important.
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November 1983
Research Papers
Parameter Sensitivity Analysis and Improvement of a Two-Layer Arterial Wall Model
W. W. von Maltzahn
W. W. von Maltzahn
Biomedical Engineering Program, The University of Texas at Arlington, Arlington, Tex. 76019
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W. W. von Maltzahn
Biomedical Engineering Program, The University of Texas at Arlington, Arlington, Tex. 76019
J Biomech Eng. Nov 1983, 105(4): 389-392 (4 pages)
Published Online: November 1, 1983
Article history
Received:
September 15, 1982
Revised:
June 15, 1983
Online:
June 15, 2009
Citation
von Maltzahn, W. W. (November 1, 1983). "Parameter Sensitivity Analysis and Improvement of a Two-Layer Arterial Wall Model." ASME. J Biomech Eng. November 1983; 105(4): 389–392. https://doi.org/10.1115/1.3138437
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