The left ventricle function is to pump the oxygenated blood through the circulatory system. Ejection fraction is the main noninvasive parameter for detecting heart disease (healthy >55%), and it is thought to be the main parameter affecting efficiency. However, the effects of other parameters on efficiency have yet to be investigated. We investigate the effect of heart rate and left ventricle shape by carrying out 3D numerical simulations of a left ventricle at different heart rates and perturbed geometries under constant, normal ejection fraction. The simulation using the immersed boundary method provide the 3D flow and pressure fields, which enable direct calculation of a new hemodynamic efficiency (H-efficiency) parameter, which does not depend on any reference pressure. The H-efficiency is defined as the ratio of flux of kinetic energy (useful power) to the total cardiac power into the left ventricle control volume. Our simulations show that H-efficiency is not that sensitive to heart rate but is maximized at around normal heart rate (72 bpm). Nevertheless, it is more sensitive to the shape of the left ventricle, which affects the H-efficiency by as much as 15% under constant ejection fraction.
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November 2015
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The Role of Shape and Heart Rate on the Performance of the Left Ventricle
Zeying Song,
Zeying Song
Mechanical and Aerospace Engineering Department,
University at Buffalo,
State University of New York,
Buffalo, NY 14260
University at Buffalo,
State University of New York,
Buffalo, NY 14260
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Iman Borazjani
Iman Borazjani
Mechanical and Aerospace Engineering Department,
University at Buffalo,
State University of New York,
Buffalo, NY 14260
e-mail: iman@buffalo.edu
University at Buffalo,
State University of New York,
Buffalo, NY 14260
e-mail: iman@buffalo.edu
Search for other works by this author on:
Zeying Song
Mechanical and Aerospace Engineering Department,
University at Buffalo,
State University of New York,
Buffalo, NY 14260
University at Buffalo,
State University of New York,
Buffalo, NY 14260
Iman Borazjani
Mechanical and Aerospace Engineering Department,
University at Buffalo,
State University of New York,
Buffalo, NY 14260
e-mail: iman@buffalo.edu
University at Buffalo,
State University of New York,
Buffalo, NY 14260
e-mail: iman@buffalo.edu
1Corresponding author.
Manuscript received October 30, 2014; final manuscript received August 21, 2015; published online September 16, 2015. Assoc. Editor: Alison Marsden.
J Biomech Eng. Nov 2015, 137(11): 114501 (6 pages)
Published Online: September 16, 2015
Article history
Received:
October 30, 2014
Revised:
August 21, 2015
Citation
Song, Z., and Borazjani, I. (September 16, 2015). "The Role of Shape and Heart Rate on the Performance of the Left Ventricle." ASME. J Biomech Eng. November 2015; 137(11): 114501. https://doi.org/10.1115/1.4031468
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