Aneurysmal recanalization and coil compaction after coil embolization of intracranial aneurysms are seen in as many as 40% of cases. Higher packing density has been suggested to reduce both coil compaction and recanalization. Basilar bifurcation aneurysms remain a challenge due possibly to the hemodynamics of this specific aneurysm/parent vessel architecture, which subjects the coil mass at the aneurysm neck to elevated and repetitive impingement forces. In the present study, we propose a new modeling strategy that facilitates a better understanding of the complex interactions between detachable coils and the local blood flow. In particular, a semiheuristic porous media set of equations used to describe the intra-aneurysmal flow is coupled to the incompressible Navier–Stokes equations governing the dynamics of the flow in the involved vessels. The resulting system of equations is solved in a strongly coupled manner using a finite element formulation. Our results suggest that there is a complex interaction between the local hemodynamics and intra-aneurysmal flow that induces significant forces on the coil mass. Although higher packing densities have previously been advocated to reduce coil compaction, our simulations suggest that lower permeability of the coil mass at a given packing density could also promote faster intra-aneurysmal thrombosis due to increased residence times.
Skip Nav Destination
Article navigation
December 2007
Research Papers
Modeling the Interaction of Coils With the Local Blood Flow After Coil Embolization of Intracranial Aneurysms
Kyung Se Cha,
Kyung Se Cha
Department of Mechanical Engineering,
University of Maryland
, College Park, MD 20742
Search for other works by this author on:
Elias Balaras,
Elias Balaras
Department of Mechanical Engineering,
University of Maryland
, College Park, MD 20742
Search for other works by this author on:
Baruch B. Lieber,
Baruch B. Lieber
Department of Biomedical Engineering, and Department of Radiology,
University of Miami
, Miami, FL 33146
Search for other works by this author on:
Chander Sadasivan,
Chander Sadasivan
Department of Biomedical Engineering, and Department of Radiology,
University of Miami
, Miami, FL 33146
Search for other works by this author on:
Ajay K. Wakhloo
Ajay K. Wakhloo
Department of Radiology, Neurosurgery, and Neurology,
University of Massachusetts Medical School
, Worcester, MA 01655
Search for other works by this author on:
Kyung Se Cha
Department of Mechanical Engineering,
University of Maryland
, College Park, MD 20742
Elias Balaras
Department of Mechanical Engineering,
University of Maryland
, College Park, MD 20742
Baruch B. Lieber
Department of Biomedical Engineering, and Department of Radiology,
University of Miami
, Miami, FL 33146
Chander Sadasivan
Department of Biomedical Engineering, and Department of Radiology,
University of Miami
, Miami, FL 33146
Ajay K. Wakhloo
Department of Radiology, Neurosurgery, and Neurology,
University of Massachusetts Medical School
, Worcester, MA 01655J Biomech Eng. Dec 2007, 129(6): 873-879 (7 pages)
Published Online: April 23, 2007
Article history
Received:
July 30, 2006
Revised:
April 23, 2007
Citation
Cha, K. S., Balaras, E., Lieber, B. B., Sadasivan, C., and Wakhloo, A. K. (April 23, 2007). "Modeling the Interaction of Coils With the Local Blood Flow After Coil Embolization of Intracranial Aneurysms." ASME. J Biomech Eng. December 2007; 129(6): 873–879. https://doi.org/10.1115/1.2800773
Download citation file:
Get Email Alerts
Cited By
Related Articles
Particle-Hemodynamics Simulations and Design Options for Surgical Reconstruction of Diseased Carotid Artery Bifurcations
J Biomech Eng (April,2004)
The Evolution of the External Left Ventricular Assist Device
J. Med. Devices (June,2010)
Numerical Simulation of Local Blood Flow in the Carotid and Cerebral Arteries Under Altered Gravity
J Biomech Eng (April,2006)
Metabolic Model of Autoregulation in the Circle of Willis
J Biomech Eng (June,2006)
Related Proceedings Papers
Related Chapters
Introduction
Nanoparticles and Brain Tumor Treatment
Experimental Studies
Nanoparticles and Brain Tumor Treatment
Conclusions
Nanoparticles and Brain Tumor Treatment