Although right-ventricular (RV) function is an important determinant of cardio-pulmonary performance in health and disease, RV myocardium biomechanical function has received little attention. In particular, no multiaxial data of the full-thickness RV have been reported for the passive or active myocardial states, for either normal or pathological conditions. Since an understanding of tissue-level biomechanical behavior is integral to connecting cellular behavior to organ-level performance, investigations into the RV myocardial stress-strain relationship are central in providing this link. For example, ventricular wall stress is considered to be a major driver of ventricular remodeling, and thus a better understanding of how wall stress and deformation are linked would provide unique insight into the mechanisms of RV function and ultimately failure in disease. Such knowledge would have direct applicability to improving methods to detect RV dysfunction, predicting response to disease-specific therapies and improving the timing of therapy if or when needed. Here, we present the first report on the multiaxial biomechanical behavior of viable full-thickness right-ventricular free wall (RVFW) myocardium and our initial efforts in developing a structural constitutive model for this remarkable tissue.
Skip Nav Destination
ASME 2011 Summer Bioengineering Conference
June 22–25, 2011
Farmington, Pennsylvania, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5458-7
PROCEEDINGS PAPER
A Structural Constitutive Model for Right Ventricular Myocardium
Daniela Valdez-Jasso,
Daniela Valdez-Jasso
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Marc A. Simon,
Marc A. Simon
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Michael S. Sacks
Michael S. Sacks
University of Pittsburgh, Pittsburgh, PA
Search for other works by this author on:
Daniela Valdez-Jasso
University of Pittsburgh, Pittsburgh, PA
Marc A. Simon
University of Pittsburgh, Pittsburgh, PA
Michael S. Sacks
University of Pittsburgh, Pittsburgh, PA
Paper No:
SBC2011-53956, pp. 155-156; 2 pages
Published Online:
July 17, 2013
Citation
Valdez-Jasso, D, Simon, MA, & Sacks, MS. "A Structural Constitutive Model for Right Ventricular Myocardium." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 155-156. ASME. https://doi.org/10.1115/SBC2011-53956
Download citation file:
11
Views
Related Proceedings Papers
Related Articles
Myocardial Material Parameter Estimation—A Comparative Study for Simple Shear
J Biomech Eng (October,2006)
Simulated Bioprosthetic Heart Valve Deformation under Quasi-Static Loading
J Biomech Eng (November,2005)
Obstruction-Induced Pulmonary Vascular Remodeling
J Biomech Eng (November,2011)
Related Chapters
Experimental Studies
Nanoparticles and Brain Tumor Treatment
Occlusion Identification and Relief within Branched Structures
Biomedical Applications of Vibration and Acoustics in Therapy, Bioeffect and Modeling
Introduction
Nanoparticles and Brain Tumor Treatment