In Vitro Phase-Contrast Magnetic Resonance Investigation on Development of Human Carotid Sinus in Young Age

The morphology of adult carotid sinus and atherosclerosis are major risk factors for ischemic stroke. It has been reported that the function of carotid sinus is pressure sensing and the regulation of heart rate. Seong and colleagues reported the lifelong development of carotid sinus morphology from infancy to maturity using post-image processed digital subtraction angiograms from 36 patients, ages from newborn to 36 years old [1]. The study unveiled the substantial growth of the internal carotid artery (ICA) with aging and the development of a carotid sinus at the root of the ICA during late adolescence. However, the development of the carotid sinus with associated hemodynamics is not clearly understood yet.