Fractional Flow Reserve (FFR) is an important indicator for the hemodynamic significance of a coronary stenosis . The FFR is defined as the pressure drop over the stenosis under hyperemia. The pressure drop, and thus the FFR, depends on both the geometry and flow. In clinical practice, the FFR is measured with a pressure wire under administration of adenosine and intervention is warranted if the FFR is below 0.8.
- Bioengineering Division
Fractional Flow Reserve Estimation in Coronary Arteries by Forward Geometrical Modeling
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Schrauwen, JTC, Wentzel, JJ, van der Steen, AFW, & Gijsen, FJH. "Fractional Flow Reserve Estimation in Coronary Arteries by Forward Geometrical Modeling." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT19A003. ASME. https://doi.org/10.1115/SBC2013-14171
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