It is often important, for diagnostic purposes, to evaluate quantitatively the motion undergone by a biological structure, starting from a viable tomographic imaging technique, such as Computed Tomography (CT) or Magnetic Resonance (MR). This is often associated with the need of the clinical personnel to perform an evaluation of a risk factor associated with pathology, e.g. ventricle performance . As of today, the problem has been approached by using the magnetic resonance (MR) tagging technique  or experimentally by determining the location of a series of surgically implanted markers in each temporal phase . The latter procedure is naturally very invasive, while MR tagging requires the use of sophisticated MR sequences that are rarely employed in standard care. Multi-detector row computer tomography (CT) scanners (routinely used in cardiac pathology diagnosis) as well as routine cine-MR sequences, on the other hand, allow dynamic imaging of the heart and large vessels with cardiac gating. In order to exploit these dynamic sequences, we have developed a tag-less method to estimate local strains from dynamic tomography gated images.
- Bioengineering Division
A Feature-Based Morphing Methodology for In-Vivo Strain Assessment in Biological Structures
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Satriano, A, Rivolo, S, & Di Martino, ES. "A Feature-Based Morphing Methodology for In-Vivo Strain Assessment in Biological Structures." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT13A028. ASME. https://doi.org/10.1115/SBC2013-14820
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