The microcirculation in the fascia of rat spinotrapezius muscle is studied using a computational approach that accounts for the shear- and hematocrit-dependent rheology of blood . The simulations are based on a realistic network reconstruction derived from microscopic images of the fascia. The model includes fundamental aspects about passive properties of microvessels  as well as active myogenic constriction in arterioles . We also present the development of a software tool to perform a spatial analysis of the hemodynamic results. This tool provides local information about the flow properties within a spatial microvessel network map in order to optimize the comparison with experiments. A review can be found in .
- Bioengineering Division
Investigation of the Spatial Structure of the Microcirculation in a Capillary Bundle From Rat Spinotrapezius Muscle Tissue
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Jacobitz, FG, Yamamura, NL, & Schmid-Schönbein, GW. "Investigation of the Spatial Structure of the Microcirculation in a Capillary Bundle From Rat Spinotrapezius Muscle Tissue." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT13A003. ASME. https://doi.org/10.1115/SBC2013-14107
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