When an arterial wall is injured, white clots form rapidly to prevent blood loss. In addition to hemostasis, under pathophysiological conditions, white clots can occlude atherosclerotic arteries. Such occlusive clots can cause ischemic cardiac arrest in less than an hour[1, 2]. Determining the predominant rate limiting processes governing thrombosis growth rate can guide us in identifying patients at increased risk of atherothrombosis.
- Bioengineering Division
Effects of Channel Size and Shear Rate on Platelet Margination
Mehrabadi, M, Aidun, CK, & Ku, DN. "Effects of Channel Size and Shear Rate on Platelet Margination." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT05A012. ASME. https://doi.org/10.1115/SBC2013-14599
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