Pelvic organ prolapse (POP) is defined as the descent of the pelvic organs into the vaginal canal. POP is a widespread condition among women, with a 7% lifetime risk for a single operation1. For surgical treatment, polypropylene mesh is often implanted to restore support to the pelvic organs. However, up to 20% of those who undergo surgery with mesh will require repeat operations for recurrent symptoms or complications2. One of the most common complications is mesh erosion3. Erosion is characterized by degeneration of the native vaginal tissue in contact with the mesh, resulting in the mesh migrating through the vagina. Though the cause of mesh erosion is undefined, surgeons have described this complication by the appearance of mesh “contraction”, “buckling”, “wrinkling”, and/or “bunching”. Some have even described this as an “accordion effect”.
- Bioengineering Division
The Impact of Boundary Conditions on Surface Curvature Measurements of Polypropylene Mesh in Response to Uniaxial Loading
Barone, WR, Amini, R, Maiti, S, Moalli, P, & Abramowitch, S. "The Impact of Boundary Conditions on Surface Curvature Measurements of Polypropylene Mesh in Response to Uniaxial Loading." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT05A011. ASME. https://doi.org/10.1115/SBC2013-14598
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