Human respiratory mucus has non-Newtonian rheological properties of viscoelasticity, shear-thinning and yield stress. They play significant roles in mucus clearance by ciliary motion as well as cough [5,7,9]. Mucus is hypersecreted in such lung diseases as cystic fibrosis and asthma. Mucus hypersecretion damages mucus clearance mechanism , and more likely causes plugs to block partial or total airways .
- Bioengineering Division
Rheology Effects on Mucus Plug Rupture
- Views Icon Views
- Share Icon Share
- Search Site
Hu, Y, Bian, S, Filoche, M, Grotberg, JC, Takayama, S, & Grotberg, JB. "Rheology Effects on Mucus Plug Rupture." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT05A009. ASME. https://doi.org/10.1115/SBC2013-14507
Download citation file: