Annual mortality from ruptured abdominal aortic aneurysm (AAA) in the United States alone is approximately 150,000, which is currently ranked as the 13th leading cause of death and the 10th leading cause of death in men over 55 years of age [1]. The vascular surgeon needs to weigh the risk of AAA rupture against the risk of surgical intervention to decide the best course of treatment. Several steps are involved when using computational techniques to evaluate risk of rupture [2], namely medical image segmentation, 3D reconstruction, finite element mesh generation, derivation of boundary conditions, specification of tissue material properties, etc. Currently, computational analysis of AAA biomechanics includes the use of multiple third-party commercial software tools to accomplish each of these steps, which makes its clinical implementation impractical, time-consuming and requiring to interface multiple software tools as this demands an engineering skill set. Additionally, the versatility of general purpose off-the-shelf software comes at the cost of simplifying assumptions regarding geometric modeling, limited user control and boundary conditions. This makes subsequent computational results vulnerable to inaccuracies. In this work, we describe the software tool AAAVASC, built on a MATLAB platform, with an integrated approach for image-based modeling and a novel pipeline that facilitates both geometry quantification and computational analysis of AAA biomechanics.
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ASME 2012 Summer Bioengineering Conference
June 20–23, 2012
Fajardo, Puerto Rico, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4480-9
PROCEEDINGS PAPER
A Comprehensive Tool for Patient-Specific AAA Geometry and Biomechanics Assessment
S. S. Raut,
S. S. Raut
Carnegie Mellon University, Pittsburgh, PA
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S. Chandra,
S. Chandra
University of Notre Dame, Notre Dame, IN
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J. Shum,
J. Shum
Carnegie Mellon University, Pittsburgh, PA
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E. S. Di Martino,
E. S. Di Martino
The University of Calgary, Calgary, AB, Canada
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T. Doehring,
T. Doehring
Drexel University, Philadelphia, PA
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A. Jana,
A. Jana
Pittsburgh Supercomputing Center, Pittsburgh, PA
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E. A. Finol
E. A. Finol
The University of Texas at San Antonio, San Antonio, TX
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S. S. Raut
Carnegie Mellon University, Pittsburgh, PA
S. Chandra
University of Notre Dame, Notre Dame, IN
J. Shum
Carnegie Mellon University, Pittsburgh, PA
P. Liu
Carnegie Mellon University, Pittsburgh, PA
E. S. Di Martino
The University of Calgary, Calgary, AB, Canada
T. Doehring
Drexel University, Philadelphia, PA
A. Jana
Pittsburgh Supercomputing Center, Pittsburgh, PA
E. A. Finol
The University of Texas at San Antonio, San Antonio, TX
Paper No:
SBC2012-80397, pp. 901-902; 2 pages
Published Online:
July 19, 2013
Citation
Raut, SS, Chandra, S, Shum, J, Liu, P, Di Martino, ES, Doehring, T, Jana, A, & Finol, EA. "A Comprehensive Tool for Patient-Specific AAA Geometry and Biomechanics Assessment." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 901-902. ASME. https://doi.org/10.1115/SBC2012-80397
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