Embryonic cardiac cells are constantly exposed to biomechanical environments including cyclic stretch and wall shear stress (WSS), which regulate behaviors of cardiac cells, critical to heart development and function [1]. Disturbances in biomechanical environment may contribute to the heart defects that affect 1% of newborns each year in US. However, changes in the biomechanical signals that affect heart development remain undescribed, partly due to a lack of methodology to quantify the biomechanical environment in the embryonic heart.

This content is only available via PDF.
You do not currently have access to this content.