Embryonic cardiac cells are constantly exposed to biomechanical environments including cyclic stretch and wall shear stress (WSS), which regulate behaviors of cardiac cells, critical to heart development and function . Disturbances in biomechanical environment may contribute to the heart defects that affect 1% of newborns each year in US. However, changes in the biomechanical signals that affect heart development remain undescribed, partly due to a lack of methodology to quantify the biomechanical environment in the embryonic heart.
- Bioengineering Division
Changes in Biomechanical Environment of Cardiac Cells in Chick Embryos After Cardiac Outflow Tract Banding
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Liu, A, Thornburg, K, Wang, R, & Rugonyi, S. "Changes in Biomechanical Environment of Cardiac Cells in Chick Embryos After Cardiac Outflow Tract Banding." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 363-364. ASME. https://doi.org/10.1115/SBC2011-53732
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