Patients suffering from a transient ischemic attack (TIA) are at high risk of a stroke or recurrent TIA, with about half of all recurrent events during the seven days after a TIA occurring in the first 24 hours. These events are usually caused by thromboembolization from ruptured carotid atherosclerotic plaques. Large trials have shown that carotid endarterectomy benefits patients with high grade carotid stenosis, but the risk-to-benefit ratio was less clear-cut for symptomatic patients with moderate stenosis (50–69%). Therefore, identification of high-risk plaques within this group could significantly decrease the ratio.
- Bioengineering Division
Stress-Strain Profile of Carotid Plaque With and Without Juxtaluminal Hemorrhage/Thrombus: A Possible Mechanism for Subsequent Cerebrovascular Events
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Teng, Z, Sadat, U, & Gillard, JH. "Stress-Strain Profile of Carotid Plaque With and Without Juxtaluminal Hemorrhage/Thrombus: A Possible Mechanism for Subsequent Cerebrovascular Events." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 25-26. ASME. https://doi.org/10.1115/SBC2011-53078
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