The parametrized diastolic filling formalism is a kinematic model for early left ventricular diastolic function, and is believed to provide quantitative information on relaxation and stiffness. Application of this model in the Asklepios population provided normal values of the model parameters x0 (initial spring displacement), k (spring stiffness) and c (damping constant). In addition, a potentially important difference in c of about 20% between men and women was observed. The underlying mechanism is not clear and additional analyses are needed to verify whether or not this suggests intrinsic relaxation differences between men and women.
- Bioengineering Division
The Parametrized Diastolic Filling Formalism: Application in the Asklepios Population
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Claessens, T, Raja, MW, Pironet, A, Chirinos, J, Desaive, T, Rietzschel, E, De Buyzere, M, Van Ransbeeck, P, Verdonck, P, Gillebert, T, & Segers, P. "The Parametrized Diastolic Filling Formalism: Application in the Asklepios Population." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 185-186. ASME. https://doi.org/10.1115/SBC2011-53375
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