Hemodynamics plays an important role in the development and progression of carotid artery atherosclerotic lesions. Certain aspects of vascular geometry, which mediates local hemodynamics, might be risk factors that increase a vessel’s atherosusceptibility [1]. To further evaluate this “geometric risk factor” hypothesis, the relationship between geometric features and hemodynamic quantities thought to typify “disturbed flow” was recently investigated [2]. Fourteen intercorrelated geometric features were initially extracted from MR images of 50 carotid bifurcations, and multivariate regression based on an a priori selection of a subset of four of these geometric features was used to identify two that were predictors of disturbed hemodynamics. Here, this work is extended to simultaneously analyze the combined role of all geometric variables using factor analysis.
Skip Nav Destination
ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Prediction of Disturbed Flow by Factor Analysis of Carotid Bifurcation Geometry
Qi Zhang,
Qi Zhang
Fudan University, Shanghai, China
Duke University, Durham, NC
Search for other works by this author on:
David A. Steinman,
David A. Steinman
University of Toronto, Toronto, ON, Canada
Search for other works by this author on:
Morton H. Friedman
Morton H. Friedman
Duke University, Durham, NC
Search for other works by this author on:
Qi Zhang
Fudan University, Shanghai, China
Duke University, Durham, NC
David A. Steinman
University of Toronto, Toronto, ON, Canada
Morton H. Friedman
Duke University, Durham, NC
Paper No:
SBC2009-204798, pp. 171-172; 2 pages
Published Online:
July 19, 2013
Citation
Zhang, Q, Steinman, DA, & Friedman, MH. "Prediction of Disturbed Flow by Factor Analysis of Carotid Bifurcation Geometry." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 171-172. ASME. https://doi.org/10.1115/SBC2009-204798
Download citation file:
3
Views
Related Proceedings Papers
Related Articles
Mass Transport of Low Density Lipoprotein in Reconstructed Hemodynamic Environments of Human Carotid Arteries: The Role of Volume and Solute Flux Through the Endothelium
J Biomech Eng (April,2015)
Three-Dimensional Geometry of the Human Carotid Artery
J Biomech Eng (June,2012)
Effect of Common Carotid Artery Inlet Length on Normal Carotid Bifurcation Hemodynamics
J Biomech Eng (December,2010)
Related Chapters
Introduction
Ultrasonic Methods for Measurement of Small Motion and Deformation of Biological Tissues for Assessment of Viscoelasticity
Semiotics Connections in Design
International Conference on Future Computer and Communication, 3rd (ICFCC 2011)
A Suggested Strategy to Increase Employee Use of Protective Clothing
Performance of Protective Clothing: Fourth Volume