Fiber-Based Constitutive Model of Myocardial Scar Tissue

It has largely been accepted that collagen fibers play an important role in the mechanics of myocardial scar tissue; however, few studies have performed both mechanical and structural analysis on the same samples to confirm this. Therefore, the goal of this study was to combine both types of analysis with a structure-based constitutive model, which incorporates measured collagen fiber orientations, to gain a better understanding of the structural basis for the mechanics of two-week-old scar tissue.