In the case of vascular grafts, enhanced mechanical properties of engineered tissue constructs are required in order to function properly in mechanically-active physiologic conditions. It is proposed that a composite matrix constructed of type I collagen, fibronectin, and covalently-functionalized single-walled carbon nanotubes (SWNTs) will provide the desired mechanical properties required for the development of implantable tissues capable of withstanding high-stress environments.

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