LMPH (Radiation heat exchange tube), the key section of ethylene cracking furnace, has various failure behaviors (e.g., carbonation, vulcanization, oxidation, and deformation) because of its rigorous working conditions and complicated structure . In this paper, the ultrasonic guided wave is applicable to inspect the interior and surface of the LMPH tube. The results demonstrate that large components in the similar structure of the heat exchange bent tube bundle can be inspected effectively, efficiently, conveniently, compared with the traditional inspection method. One inspection example of an ethylene cracking furnace tube bundle is forwarded. The paper also provides an engineering application/case and valuable crafting process for the detection of similar structures by the ultrasonic guided wave method.