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Proceedings Papers

Biological Gradient Regulated Predictive Model of Long Bone Growth

Juan M. Taboas, Amy L. Lerner
Proc. ASME. IMECE97, Advances in Bioengineering, 13-14, November 16–21, 1997
Paper No: IMECE1997-0204
DOI: https://doi.org/10.1115/IMECE1997-0204
View Paper titled, Biological Gradient Regulated Predictive Model of Long Bone Growth
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Topics: Bone, Cartilage, Chondrocytes, Computer programming, Finite element analysis, Minerals, Muscle, Osteoblasts, Stress
Proceedings Papers

Microindentation of the Individual Layers of Articular Cartilage

Daehwan Shin, Jian-Hua Lin, Kyriacos Athanasiou
Proc. ASME. IMECE97, Advances in Bioengineering, 155-156, November 16–21, 1997
Paper No: IMECE1997-0275
DOI: https://doi.org/10.1115/IMECE1997-0275
View Paper titled, Microindentation of the Individual Layers of Articular Cartilage
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Topics: Cartilage, Biomechanics, Bone, Chondrocytes, Mechanical properties, Testing
Proceedings Papers

Measurement of Cartilage Fluid Pressurization in Confined Compression Cyclical Loading

Michael A. Soltz, Gerard A. Ateshian
Proc. ASME. IMECE98, Advances in Bioengineering, 23-24, November 15–20, 1998
Paper No: IMECE1998-0012
DOI: https://doi.org/10.1115/IMECE1998-0012
View Paper titled, Measurement of Cartilage Fluid Pressurization in Confined Compression Cyclical Loading
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Topics: Cartilage, Compression, Fluids, Stress, Biological tissues, Chondrocytes, Compressive stress, Creep, Hydrostatics, Relaxation (Physics)
Proceedings Papers

Effects of Aggregate Modulus Inhomogeneity on Cartilage Compressive Stress-Relaxation Behavior

C. B. Wang, V. C. Mow
Proc. ASME. IMECE98, Advances in Bioengineering, 261-262, November 15–20, 1998
Paper No: IMECE1998-0130
DOI: https://doi.org/10.1115/IMECE1998-0130
View Paper titled, Effects of Aggregate Modulus Inhomogeneity on Cartilage Compressive Stress-Relaxation Behavior
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Topics: Cartilage, Relaxation (Physics), Stress, Biological tissues, Materials properties, Bone, Chondrocytes, Viscoelasticity
Proceedings Papers

Toward Defining the Role of Ca 2+ and MAP Kinases in Fluid-Induced Shear Regulation of Aggrecan in Chondrocytes

Clark T. Hung, Changbin B. Wang, Ross Henshaw, Wilmot B. Valhmu, Mary B. Goldring
Proc. ASME. IMECE98, Advances in Bioengineering, 59-60, November 15–20, 1998
Paper No: IMECE1998-0030
DOI: https://doi.org/10.1115/IMECE1998-0030
View Paper titled, Toward Defining the Role of Ca 2+ and MAP Kinases in Fluid-Induced Shear Regulation of Aggrecan in Chondrocytes
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Topics: Chondrocytes, Fluids, Shear (Mechanics), Proteins
Proceedings Papers

Real-Time Observations of the Behavior of Cells Under Controlled Pressure and Shear Loads

Andrew Tsourkas, Gang Bao
Proc. ASME. IMECE99, Advances in Bioengineering, 115-116, November 14–19, 1999
Paper No: IMECE1999-0404
DOI: https://doi.org/10.1115/IMECE1999-0404
View Paper titled, Real-Time Observations of the Behavior of Cells Under Controlled Pressure and Shear Loads
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Topics: Pressure, Shear (Mechanics), Stress, Die cutting, Shearing (Deformation), Cardiac cycle, Chondrocytes, Compression, Deformation, Diseases
Proceedings Papers

Chondrocyte Translocation and Orientation to Applied DC Electric Fields

Robert L. Mauck, Pen-hsiu G. Chao, Beth Gilbert, Wilmot B. Valhmu, Clark T. Hung
Proc. ASME. IMECE99, Advances in Bioengineering, 117-118, November 14–19, 1999
Paper No: IMECE1999-0405
DOI: https://doi.org/10.1115/IMECE1999-0405
View Paper titled, Chondrocyte Translocation and Orientation to Applied DC Electric Fields
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Topics: Chondrocytes, Electric fields, Cartilage, Bioengineering, Biological tissues, Bone, Cornea, Fibroblasts, Maintenance, Shapes
Proceedings Papers

Osmotic Stress Initiates Intracellular Calcium Waves in Chondrocytes Through Extracellular Influx and the Inositol Phosphate Pathway

Geoffrey R. Erickson, Farshid Guilak
Proc. ASME. IMECE99, Advances in Heat and Mass Transfer in Biotechnology, 43-44, November 14–19, 1999
Paper No: IMECE1999-0580
DOI: https://doi.org/10.1115/IMECE1999-0580
View Paper titled, Osmotic Stress Initiates Intracellular Calcium Waves in Chondrocytes Through Extracellular Influx and the Inositol Phosphate Pathway
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Topics: Chondrocytes, Osmosis, Stress, Waves, Cartilage, Compression, Transients (Dynamics), Biological tissues, Fluid dynamics, Fluid pressure
Proceedings Papers

Time-Varying Effect of Ascorbate on the Compressive Modulus and Gag Content of Chondrocyte-Seeded Agarose Cultures

Robert L. Mauck, Michael A. Soltz, Beth Gilbert, Gerard A. Ateshian, Clark T. Hung, Frank J. Raia, Wilmot B. Valhmu
Proc. ASME. IMECE99, Advances in Bioengineering, 105-106, November 14–19, 1999
Paper No: IMECE1999-0399
DOI: https://doi.org/10.1115/IMECE1999-0399
View Paper titled, Time-Varying Effect of Ascorbate on the Compressive Modulus and Gag Content of Chondrocyte-Seeded Agarose Cultures
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Topics: Agar, Chondrocytes, Disks, Cartilage, Mechanical properties, Assaying, Biological tissues
Proceedings Papers

Direct Hydraulic Permeability Measurements of Agarose Hydrogels Used as Cell Scaffolds

Michael A. Soltz, Anna Stankiewicz, Gerard Ateshian, Robert L. Mauck, Clark T. Hung
Proc. ASME. IMECE99, Advances in Bioengineering, 229-230, November 14–19, 1999
Paper No: IMECE1999-0461
DOI: https://doi.org/10.1115/IMECE1999-0461
View Paper titled, Direct Hydraulic Permeability Measurements of Agarose Hydrogels Used as Cell Scaffolds
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Topics: Agar, Hydrogels, Permeability, Fluids, Chondrocytes, Cartilage, Fluid dynamics, Bearings, Compacting, Ions
Proceedings Papers

The Effects of Osmotic Pressure on the Viscoelastic and Physical Properties of Articular Chondrocytes

Farshid Guilak, H. Ping Ting-Beall
Proc. ASME. IMECE99, Advances in Bioengineering, 103-104, November 14–19, 1999
Paper No: IMECE1999-0398
DOI: https://doi.org/10.1115/IMECE1999-0398
View Paper titled, The Effects of Osmotic Pressure on the Viscoelastic and Physical Properties of Articular Chondrocytes
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Topics: Chondrocytes, Osmosis, Pressure, Stress, Cartilage, Compression, Deformation, Maintenance, Mechanical properties, Signals
Proceedings Papers

Development of an In Vivo Rabbit Model for Cartilage Trauma: Influence of Impact Stress Magnitude on Chondrocyte Death

Dejan Milentijevic, Allan Liew, Peter A. Torzilli
Proc. ASME. IMECE2001, Advances in Bioengineering, 125-126, November 11–16, 2001
Paper No: IMECE2001/BED-23062
DOI: https://doi.org/10.1115/IMECE2001/BED-23062
View Paper titled, Development of an In Vivo Rabbit Model for Cartilage Trauma: Influence of Impact Stress Magnitude on Chondrocyte Death
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Topics: Cartilage, Chondrocytes, Stress, Biological tissues, Damage, Potential energy, Wounds
Proceedings Papers

Mechanical Loading Modulates Gene Expression in Chondrocyte-Seeded Agarose Hydrogels

Sansan S. Lo, Robert L. Mauck, Sara L. Seyhan, Glyn D. Palmer, Van C. Mow, Clark T. Hung
Proc. ASME. IMECE2001, Advances in Bioengineering, 291-292, November 11–16, 2001
Paper No: IMECE2001/BED-23145
DOI: https://doi.org/10.1115/IMECE2001/BED-23145
View Paper titled, Mechanical Loading Modulates Gene Expression in Chondrocyte-Seeded Agarose Hydrogels
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Topics: Agar, Chondrocytes, Hydrogels, Cartilage, Stress, Biological tissues, Bearings, Bioreactors, Compression, Dynamic testing (Materials)
Proceedings Papers

Temporal Development of Material Properties in Free Swelling Chondrocyte-Seeded Agarose Constructs

Terri-Ann N. Kelly, Christopher C.-B. Wang, Nadeen O. Chahine, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. IMECE2001, Advances in Bioengineering, 289-290, November 11–16, 2001
Paper No: IMECE2001/BED-23144
DOI: https://doi.org/10.1115/IMECE2001/BED-23144
View Paper titled, Temporal Development of Material Properties in Free Swelling Chondrocyte-Seeded Agarose Constructs
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Topics: Agar, Chondrocytes, Materials properties, Biological tissues, Biomechanics, Cartilage, Displacement, Hydrogels, Microscopy, Poisson ratio
Proceedings Papers

Dynamic Hydrostatic Pressurization Increases Matrix Gene Expression by Chondrocytes in 3D Culture

Robert L. Mauck, Michael A. Soltz, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. IMECE2001, Advances in Bioengineering, 295-296, November 11–16, 2001
Paper No: IMECE2001/BED-23147
DOI: https://doi.org/10.1115/IMECE2001/BED-23147
View Paper titled, Dynamic Hydrostatic Pressurization Increases Matrix Gene Expression by Chondrocytes in 3D Culture
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Topics: Chondrocytes, Hydrostatics, Cartilage, Hydrostatic pressure, Pressure, Stress, Bearings, Bone, Deformation, Hydrogels
Proceedings Papers

Depth-Dependent Material Property Inhomogeneities Affect the Deformation and Electric Fields in the Chondrocytes and Extracellular Matrix During Compression

D. D. Sun, V. C. Mow, W. M. Lai, X. E. Guo
Proc. ASME. IMECE2001, Advances in Bioengineering, 119-120, November 11–16, 2001
Paper No: IMECE2001/BED-23059
DOI: https://doi.org/10.1115/IMECE2001/BED-23059
View Paper titled, Depth-Dependent Material Property Inhomogeneities Affect the Deformation and Electric Fields in the Chondrocytes and Extracellular Matrix During Compression
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Topics: Chondrocytes, Compression, Deformation, Electric fields, Materials properties, Signals, Cartilage, Electric potential, Osmosis, Fluids
Proceedings Papers

An Axisymmetric Elastic Layered Half-Space Model for Micropipette Aspiration of the Chondrocyte Pericellular Matrix

Leonidas G. Alexopoulos, Mansoor A. Haider, Farshid Guilak
Proc. ASME. IMECE2001, Advances in Bioengineering, 313-314, November 11–16, 2001
Paper No: IMECE2001/BED-23156
DOI: https://doi.org/10.1115/IMECE2001/BED-23156
View Paper titled, An Axisymmetric Elastic Layered Half-Space Model for Micropipette Aspiration of the Chondrocyte Pericellular Matrix
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Topics: Chondrocytes, Biological tissues, Cartilage, Bearings, Stress
Proceedings Papers

Microstructural Factors in Neocartilage Function

Jack L. Lewis
Proc. ASME. IMECE2000, Advances in Bioengineering, 39-40, November 5–10, 2000
Paper No: IMECE2000-2504
DOI: https://doi.org/10.1115/IMECE2000-2504
View Paper titled, Microstructural Factors in Neocartilage Function
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Topics: Biological tissues, Biomedicine, Cartilage, Chondrocytes, Manufacturing, Materials science, Mechanical properties, Tissue engineering
Proceedings Papers

Effects of Inhomogeneous Fixed Charge Density on the Electrical Signals for Chondrocytes in Cartilage

W. M. Lai, D. D. Sun, G. A. Ateshian, X. E. Guo, V. C. Mow
Proc. ASME. IMECE2000, Mechanics in Biology, 201-213, November 5–10, 2000
Paper No: IMECE2000-1931
DOI: https://doi.org/10.1115/IMECE2000-1931
View Paper titled, Effects of Inhomogeneous Fixed Charge Density on the Electrical Signals for Chondrocytes in Cartilage
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Topics: Cartilage, Chondrocytes, Density, Signals, Biological tissues, Diffusion (Physics), Electric potential, Fluids, Bioreactors, Biotechnology
Proceedings Papers

Changes in the Mechano-Electrochemical Environment in the Extracellular Matrix Surrounding Chondrocytes

V. C. Mow, X. E. Guo, D. D. Sun, W. M. Lai
Proc. ASME. IMECE2000, Mechanics in Biology, 215-228, November 5–10, 2000
Paper No: IMECE2000-1932
DOI: https://doi.org/10.1115/IMECE2000-1932
View Paper titled, Changes in the Mechano-Electrochemical Environment in the Extracellular Matrix Surrounding Chondrocytes
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Topics: Chondrocytes, Compression, Flow (Dynamics), Pressure, Cartilage, Fluid dynamics, Osmosis, Biomechanics, Compacting, Deformation