Mechanical characterization of human cartilage anlagen is required in order to effectively model congenital musculoskeletal deformities. Such modeling can effectively explore the effect of treatment procedures and potentially suggest enhanced treatment methods. We therefore determined the stress relaxation behavior of cartilage plugs obtained from third-trimester still-born fetuses in unconfined and confined compression geometries. The material parameters determined were the aggregate modulus HA = 0.15 ± 0.07 MPa, permeability coefficients k0 = 2.01 ± 0.8 × 10−14m4N−1s−1 and M = 4.6 ± 1.0, Young’s modulus Es = 0.06 ± 0.03 MPa, and Poisson’s ratio ν = 0.4 ± 0.06. As compared to adult articular cartilage, stiffness was an order of magnitude lower than the values reported in the literature, inferring the relative softness of the tissue; and the permeability was an order of magnitude higher indicating relative ease of flow in the tissue. Poisson’s ratio also was close to the higher end of the range found in previous studies. Such material is expected to deform and relax to larger extents.
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ASME 2008 International Mechanical Engineering Congress and Exposition
October 31–November 6, 2008
Boston, Massachusetts, USA
Conference Sponsors:
- ASME
ISBN:
978-0-7918-4863-0
PROCEEDINGS PAPER
Characterization of Compressive Behavior of Developing Human Talus
Roza Mahmoodian,
Roza Mahmoodian
Drexel University, Philadelphia, PA
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Jeremi Leasure,
Jeremi Leasure
Drexel University, Philadelphia, PA
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Sorin Siegler,
Sorin Siegler
Drexel University, Philadelphia, PA
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Franco Capaldi
Franco Capaldi
Drexel University, Philadelphia, PA
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Roza Mahmoodian
Drexel University, Philadelphia, PA
Jeremi Leasure
Drexel University, Philadelphia, PA
Sorin Siegler
Drexel University, Philadelphia, PA
Franco Capaldi
Drexel University, Philadelphia, PA
Paper No:
IMECE2008-67851, pp. 699-706; 8 pages
Published Online:
August 26, 2009
Citation
Mahmoodian, R, Leasure, J, Siegler, S, & Capaldi, F. "Characterization of Compressive Behavior of Developing Human Talus." Proceedings of the ASME 2008 International Mechanical Engineering Congress and Exposition. Volume 2: Biomedical and Biotechnology Engineering. Boston, Massachusetts, USA. October 31–November 6, 2008. pp. 699-706. ASME. https://doi.org/10.1115/IMECE2008-67851
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