In this work, three layers of human aorta, i.e. intima, media and adventitia, obtained from a 9 mm CryoValve® aortic valve allograft, were tested along both axial and circumferential directions. Preconditioning with a stretch ratio of 1.35 was used to mimic the physiological pulsatile loading conditions of the tissue. Results suggested that the stiffness along circumferential direction is generally larger than axial direction in each of the three layers. In all three layers, the media layer is the stiffest, and the adventitia layer is the softest regardless of testing directions. The anisotropic, nonlinear elastic mechanical behavior of each layer from the aortic valve allograft could help better understand the compliance mismatch between the allograft and native arterial tissue.
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ASME 2012 International Mechanical Engineering Congress and Exposition
November 9–15, 2012
Houston, Texas, USA
Conference Sponsors:
- ASME
ISBN:
978-0-7918-4518-9
PROCEEDINGS PAPER
Mechanical Characterization of the Layer-Specific Human Aorta
Shijia Zhao,
Shijia Zhao
University of Nebraska-Lincoln, Lincoln, NE
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Linxia Gu,
Linxia Gu
University of Nebraska-Lincoln, Lincoln, NE
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Shengmao Lin
Shengmao Lin
University of Nebraska-Lincoln, Lincoln, NE
Search for other works by this author on:
Shijia Zhao
University of Nebraska-Lincoln, Lincoln, NE
Linxia Gu
University of Nebraska-Lincoln, Lincoln, NE
Shengmao Lin
University of Nebraska-Lincoln, Lincoln, NE
Paper No:
IMECE2012-87083, pp. 269-270; 2 pages
Published Online:
October 8, 2013
Citation
Zhao, S, Gu, L, & Lin, S. "Mechanical Characterization of the Layer-Specific Human Aorta." Proceedings of the ASME 2012 International Mechanical Engineering Congress and Exposition. Volume 2: Biomedical and Biotechnology. Houston, Texas, USA. November 9–15, 2012. pp. 269-270. ASME. https://doi.org/10.1115/IMECE2012-87083
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