Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.
Nanomechanical Microcantilevers for In-Vitro Biomolecular Detection
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Eom, K, Kwon, TY, Park, J, Na, S, Yoon, DS, & Kim, TS. "Nanomechanical Microcantilevers for In-Vitro Biomolecular Detection." Proceedings of the ASME 2007 International Mechanical Engineering Congress and Exposition. Volume 10: Mechanics of Solids and Structures, Parts A and B. Seattle, Washington, USA. November 11–15, 2007. pp. 821-842. ASME. https://doi.org/10.1115/IMECE2007-41290
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