Nanomechanical microcantilevers have enabled the sensitive label-free detection of chemical and/or biological molecules. In recent years, resonating microcantilevers have achieved the unprecedented sensitivity in detecting molecules. In this article, we review our current works on the label-free detection of biomolecules based on resonating microcantilevers. Our piezoelectric thick film microcantilevers exhibit the relatively high quality factor in a viscous liquid, indicating the potential of our cantilever to in situ biosensor applications for real-time detection of biomolecular interactions. It is shown that our microcantilevers allow the noise-free real-time monitoring of biomolecular recognitions, providing the insight into kinetics of biomolecular recognitions.
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ASME 2007 International Mechanical Engineering Congress and Exposition
November 11–15, 2007
Seattle, Washington, USA
Conference Sponsors:
- ASME
ISBN:
0-7918-4304-1
PROCEEDINGS PAPER
Nanomechanical Microcantilevers for In-Vitro Biomolecular Detection
Kilho Eom,
Kilho Eom
Korea Institute of Science and Technology, Seoul, South Korea
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Tae Yun Kwon,
Tae Yun Kwon
Korea Institute of Science and Technology, Seoul, South Korea
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Jinsung Park,
Jinsung Park
Korea Institute of Science and Technology, Seoul, South Korea
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Sungsoo Na,
Sungsoo Na
Korea University, Seoul, South Korea
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Dae Sung Yoon,
Dae Sung Yoon
Korea Institute of Science and Technology, Seoul, South Korea
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Tae Song Kim
Tae Song Kim
Korea Institute of Science and Technology, Seoul, South Korea
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Kilho Eom
Korea Institute of Science and Technology, Seoul, South Korea
Tae Yun Kwon
Korea Institute of Science and Technology, Seoul, South Korea
Jinsung Park
Korea Institute of Science and Technology, Seoul, South Korea
Sungsoo Na
Korea University, Seoul, South Korea
Dae Sung Yoon
Korea Institute of Science and Technology, Seoul, South Korea
Tae Song Kim
Korea Institute of Science and Technology, Seoul, South Korea
Paper No:
IMECE2007-41290, pp. 821-842; 22 pages
Published Online:
May 22, 2009
Citation
Eom, K, Kwon, TY, Park, J, Na, S, Yoon, DS, & Kim, TS. "Nanomechanical Microcantilevers for In-Vitro Biomolecular Detection." Proceedings of the ASME 2007 International Mechanical Engineering Congress and Exposition. Volume 10: Mechanics of Solids and Structures, Parts A and B. Seattle, Washington, USA. November 11–15, 2007. pp. 821-842. ASME. https://doi.org/10.1115/IMECE2007-41290
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