A simplified model of the cerebrospinal fluid (CSF) system with compliant fluid filled syrinx has been constructed, tested, and verified to closely mimic the in-vivo flow conditions observed through MRI imaging of the pathological CSF system with syringomyelia. The model is subjected to a MRI derived CSF flow waveform from a patient with Syringomyelia through use of a computer controlled pulsatile pump. Model geometry, flow waveform, and spinal cord compliance are obtained at three axial locations along the system through MRI image processing techniques. MRI testing was conducted with the syrinx open and closed to the external environment. Results indicate that the internal and external flow waveforms were in opposite directions when the syrinx was closed and in unison when the syrinx was open. The observed flow waveform and compliance measurements closely mimicked the in-vivo case when the syrinx is open to the external environment.
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ASME 2004 International Mechanical Engineering Congress and Exposition
November 13–19, 2004
Anaheim, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
0-7918-4703-9
PROCEEDINGS PAPER
Construction and Validation of a Complaint Model of the Cerebrospinal Fluid System With Fluid Filled Syrinx
Bryn A. Martin,
Bryn A. Martin
University of Illinois at Chicago
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Wojciech Kalata,
Wojciech Kalata
University of Illinois at Chicago
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Francis Loth,
Francis Loth
University of Illinois at Chicago
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Thomas J. Royston
Thomas J. Royston
University of Illinois at Chicago
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Bryn A. Martin
University of Illinois at Chicago
Wojciech Kalata
University of Illinois at Chicago
John N. Oshinski
Emory University
Francis Loth
University of Illinois at Chicago
Thomas J. Royston
University of Illinois at Chicago
Paper No:
IMECE2004-62033, pp. 185-186; 2 pages
Published Online:
March 24, 2008
Citation
Martin, BA, Kalata, W, Oshinski, JN, Loth, F, & Royston, TJ. "Construction and Validation of a Complaint Model of the Cerebrospinal Fluid System With Fluid Filled Syrinx." Proceedings of the ASME 2004 International Mechanical Engineering Congress and Exposition. Advances in Bioengineering. Anaheim, California, USA. November 13–19, 2004. pp. 185-186. ASME. https://doi.org/10.1115/IMECE2004-62033
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