We report the results of planning and experimental validation of femoroplasty — augmentation of mechanical properties of the bone using polymethylmethacrylate (PMMA) bone cement injection — on osteoporotic femurs. For six pairs of osteoporotic femurs, finite element (FE) models were created using computed tomography (CT) scan data and an evolutionary method was used to optimize the cement pattern in one of the models from each pair. Using a particle method and the CT data, cement diffusion was modeled for several hypothetical augmentations and the one most closely matching the optimized pattern was chosen as the best plan. We used intra-operative navigation and a custom-designed injection device to deliver the cement into the bones precisely according to the plan. All femurs were then tested mechanically in a configuration simulating a fall to the side. Augmentation with this technique resulted in an increase in the yield load (28%) and yield energy (142%) compared to the control specimens, while only 9.8ml of cement was injected on average. Results support our hypothesis that significant improvements in the mechanical properties of osteoporotic femurs can be achieved by using minimal, and hence safe, amounts of PMMA bone cement.
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ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
August 4–7, 2013
Portland, Oregon, USA
Conference Sponsors:
- Design Engineering Division
- Computers and Information in Engineering Division
ISBN:
978-0-7918-5591-1
PROCEEDINGS PAPER
Computer Assisted Femoral Augmentation: Modeling and Experimental Validation
Ehsan Basafa,
Ehsan Basafa
Johns Hopkins University, Baltimore, MD
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Ryan J. Murphy,
Ryan J. Murphy
Johns Hopkins University Applied Physics Lab, Laurel, MD
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Michael D. Kutzer,
Michael D. Kutzer
Johns Hopkins University Applied Physics Lab, Laurel, MD
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Yoshito Otake,
Yoshito Otake
Johns Hopkins University, Baltimore, MD
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Mehran Armand
Mehran Armand
Johns Hopkins University Applied Physics Lab, Laurel, MD
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Ehsan Basafa
Johns Hopkins University, Baltimore, MD
Ryan J. Murphy
Johns Hopkins University Applied Physics Lab, Laurel, MD
Michael D. Kutzer
Johns Hopkins University Applied Physics Lab, Laurel, MD
Yoshito Otake
Johns Hopkins University, Baltimore, MD
Mehran Armand
Johns Hopkins University Applied Physics Lab, Laurel, MD
Paper No:
DETC2013-13636, V004T08A010; 9 pages
Published Online:
February 12, 2014
Citation
Basafa, E, Murphy, RJ, Kutzer, MD, Otake, Y, & Armand, M. "Computer Assisted Femoral Augmentation: Modeling and Experimental Validation." Proceedings of the ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. Volume 4: 18th Design for Manufacturing and the Life Cycle Conference; 2013 ASME/IEEE International Conference on Mechatronic and Embedded Systems and Applications. Portland, Oregon, USA. August 4–7, 2013. V004T08A010. ASME. https://doi.org/10.1115/DETC2013-13636
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