We employed computational fluid dynamics (CFD) and finite element method (FEM) to investigate the hemodynamic effect of two flow-diversion strategies of cerebral aneurysm treatment: overlapping stents and dense compaction of a single stent. Three representative patient-specific aneurysms were used as test cases, and flow diverters were virtually deployed into the models. Aneurysmal hemodynamic modification by flow diverters is strongly correlated with the metal coverage rate across the aneurysm neck, and not uniquely determined by FD deployment strategies. Fusiform aneurysms may be more favorable for achieving dense compaction for increased metal coverage rate than saccuclar aneurysms. To induce high flow reduction, the overlapping strategy may be more suitable for sidewall aneurysms, and the dense compaction strategy for fusiform aneurysms.

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