A bicycle frame is optimized for the lightest weight by using genetic algorithms in this study. Stresses of five rods in the bicycle frame less than the material yielding strength with consideration of the factor of safety are the constraints. A two-dimensional model of the frame is created. Equilibrium equations are derived and loads acting on rods are determined. A known function is used to verify feasibility of the program generated. Effects of the mutation rate, the crossover rate and the number of generation on the mean and the standard deviation of the fitness value are studied. The optimal solutions with the outer diameters and the inner diameters of the front frame rods to be 0.040 m and 0.038 m, respectively, the outer diameters and the inner diameters of the rear frame rods to be 0.024 m and 0.021m, respectively, and the weight of the bicycle frame to be 0.896 kg are recommended for the bicycle frame.

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