This paper presents the research work to investigate how well we can predict system interactions at early phase of the product development process using the matrix transformation technique presented by Dong and Whitney [1] at DETC 2001. The technique to predict design information flow patterns using requirements was applied to a case study at Johnson and Johnson Ortho-clinical Diagnosis. Several Design Structure Matrices (DSM) were created. The DSM’s were compared to the system interactions that engineers actually experienced during the design process, recorded in their own DSM. The observations from this case study provided insights to the predictability of various types of product development process, and demonstrated the value of the matrix transformation process.

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