A cardiovascular stent is a cylindrical wire mesh structure that is permanently introduced into an artery during angioplasty (balloon dilatation) to act as a scaffold, thus preventing elastic recoil and/or sudden collapse of the damaged artery. While cardiovascular stents virtually eliminate elastic recoil and/or collapse of the artery, recognition of the stent as a foreign material triggers a human immune system response causing re-closure, or restenosis, of the artery. A recent advancement to counteract restenosis is to employ drug-eluting stents to locally deliver immunosuppressant and antiproliferative drugs.
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Auxetic Drug-Eluting Stent Design
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Dolla, WJS, Fricke, BA, & Becker, BR. "Auxetic Drug-Eluting Stent Design." Proceedings of the ASME 2006 Frontiers in Biomedical Devices Conference. ASME 2006 Frontiers in Biomedical Devices Conference. Irvine, California, USA. June 8–9, 2006. pp. 11-12. ASME. https://doi.org/10.1115/NANOBIO2006-18035
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